The Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town 7925, South Africa.
Cold Spring Harb Perspect Med. 2012 Aug 1;2(8):a007435. doi: 10.1101/cshperspect.a007435.
Around 2.5 million people become infected with HIV each year. This extraordinary toll on human life and public health worldwide will only be reversed with effective prevention. What's more, in the next few years, it is likely at least, that no single prevention strategy will be sufficient to contain the spread of the disease. There is a need for combination prevention as there is for combination treatment, including biomedical, behavioral, and structural interventions. Expanded HIV prevention must be grounded in a systematic analysis of the epidemic's dynamics in local contexts. Although 85% of HIV is transmitted sexually, effective combinations of prevention have been shown for people who inject drugs. Combination prevention should be based on scientifically derived evidence, with input and engagement from local communities that fosters the successful integration of care and treatment.
每年约有 250 万人感染艾滋病毒。要扭转这一给全世界人类生命和公共卫生带来巨大损失的局面,必须采取有效的预防措施。此外,在未来几年内,很可能至少没有任何单一的预防策略足以遏制疾病的传播。正如需要组合治疗一样,也需要组合预防,包括生物医学、行为和结构干预措施。扩大艾滋病毒预防工作必须立足于对当地流行情况动态的系统分析。虽然 85%的艾滋病毒是通过性途径传播的,但已证明针对注射吸毒者的预防措施具有一定效果。组合预防应基于科学依据,并得到当地社区的投入和参与,以促进治疗和关怀的成功融合。