Hansson Emma, Manjer Jonas, Svensson Henry, Brorson Håkan
Department of Clinical Sciences Malmö, Lund University, Plastic and Reconstructive Surgery, Skåne University Hospital, Malmö, Sweden.
J Plast Surg Hand Surg. 2012 Sep;46(3-4):252-6. doi: 10.3109/2000656X.2012.698417.
Dercum's disease is characterised by obesity, pronounced pain in the adipose tissue, and a number of associated symptoms. Liposuction has been suggested as a treatment. However, the effect on quality-of-life after liposuction in Dercum's disease has never been investigated. The objective of this study was to examine the quality-of-life in Dercum's disease before and after liposuction. A total of 114 women fulfilling the clinical criteria of Dercum's disease were included. Of the 114 women, 53 were operated on with liposuction and 61 were Dercum controls. In addition, 41 obese healthy women operated on with abdominoplasty were recruited as controls. Health-related quality-of-life (HRQoL) was measured with the Nottingham Health Profile (NHP) and the Psychological General Well-Being index (PGWB). The Dercum group had lower HRQoL than the abdominoplasty controls. After liposuction, a slight improvement could be seen in HRQoL in the operated patients compared with preoperatively, but it did not become as high as in the abdominoplasty patients. In conclusion, the findings could suggest that liposuction improves the quality-of-life slightly in Dercum's disease. Nonetheless, the causality is unclear and the improvement is not big enough to warrant operation.
德库姆病的特征是肥胖、脂肪组织剧痛以及一系列相关症状。抽脂术已被提议作为一种治疗方法。然而，抽脂术对德库姆病患者生活质量的影响从未被研究过。本研究的目的是检查抽脂术前和术后德库姆病患者的生活质量。共有114名符合德库姆病临床标准的女性被纳入研究。在这114名女性中，53人接受了抽脂手术，61人作为德库姆病对照组。此外，41名接受腹部整形手术的肥胖健康女性被招募作为对照组。使用诺丁汉健康量表（NHP）和心理总体幸福感指数（PGWB）来测量与健康相关的生活质量（HRQoL）。德库姆病组的HRQoL低于腹部整形手术对照组。抽脂术后，与术前相比，手术患者的HRQoL略有改善，但未达到腹部整形手术患者的水平。总之，研究结果表明抽脂术可使德库姆病患者的生活质量略有改善。尽管如此，因果关系尚不清楚，且改善程度不足以保证进行手术。
