胰岛素样生长因子II（IGF-II）对胎儿隔核移植胆碱能神经元的影响。 - Suppr | 超能文献

Effects of insulin-like growth factor II (IGF-II) on transplanted cholinergic neurons from the fetal septal nucleus.

作者信息

Gage S L, Keim S R, Low W C

机构信息

Department of Physiology and Biophysics, Indiana University School of Medicine, Indianapolis 46202-5120.

出版信息

Prog Brain Res. 1990;82:73-80. doi: 10.1016/s0079-6123(08)62592-3.

DOI:10.1016/s0079-6123(08)62592-3

Abstract

摘要

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Effects of insulin-like growth factor II (IGF-II) on transplanted cholinergic neurons from the fetal septal nucleus.胰岛素样生长因子II（IGF-II）对胎儿隔核移植胆碱能神经元的影响。

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IGF2 ameliorates amyloidosis, increases cholinergic marker expression and raises BMP9 and neurotrophin levels in the hippocampus of the APPswePS1dE9 Alzheimer's disease model mice.胰岛素样生长因子2可改善淀粉样变性，增加胆碱能标志物表达，并提高APPswePS1dE9阿尔茨海默病模型小鼠海马中的骨形态发生蛋白9和神经营养因子水平。

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Insulin-like growth factors-I and -II differentially regulate endogenous acetylcholine release from the rat hippocampal formation.胰岛素样生长因子-I和-II对大鼠海马结构中内源性乙酰胆碱释放具有不同的调节作用。

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