Petrarca Alicia M, Lengel Aaron J, Mangan Michelle N
University of Toledo College of Pharmacy and Pharmaceutical Sciences, Toledo, OH, USA.
Consult Pharm. 2012 Aug;27(8):583-6. doi: 10.4140/TCP.n.2012.583.
STOPP (Screening Tool of Older Persons' Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment) are relatively new, validated tools that increasingly are used together to identify prescribing errors in elderly patients. This article reviews two studies that have directly compared STOPP with the Beers criteria, which is the current standard tool used to identify potentially inappropriate medications (PIMs) in older patients. Both studies reveal greater correlations to adverse drug events (ADEs) with PIMs defined by STOPP than with those defined by the Beers criteria, suggesting STOPP may be more useful in practice. Additional studies are needed to confirm STOPP's greater sensitivity and to determine whether its use translates to improved patient outcomes such as decreased morbidity, mortality, and health care costs. If so, pharmacists should consider implementation of STOPP (with or without START) in practice to improve care for the elderly population.
老年人处方筛查工具（STOPP）和提醒医生正确治疗的筛查工具（START）是相对较新的、经过验证的工具，越来越多地被一起用于识别老年患者的处方错误。本文回顾了两项直接将STOPP与Beers标准进行比较的研究，Beers标准是目前用于识别老年患者潜在不适当药物（PIM）的标准工具。两项研究均显示，与Beers标准定义的PIM相比，STOPP定义的PIM与药物不良事件（ADE）的相关性更强，这表明STOPP在实践中可能更有用。需要更多的研究来证实STOPP更高的敏感性，并确定其使用是否能转化为改善患者结局，如降低发病率、死亡率和医疗保健成本。如果是这样，药剂师在实践中应考虑实施STOPP（无论是否使用START），以改善对老年人群的护理。
