Department of Surgery, University of Missouri, Columbia, Missouri, USA.
Surg Infect (Larchmt). 2012 Aug;13(4):203-8. doi: 10.1089/sur.2012.124. Epub 2012 Aug 22.
Sepsis is an excessive systemic inflammatory response activated by invasive infection. There has been substantial epidemiologic literature addressing perceived disparities in sepsis by demographic factors such as gender and race. There also have been multiple examinations of the disparities of sepsis with regard to environmental and socioeconomic factors. This paper reviews the current epidemiologic literature evaluating the association of race with the development of sepsis and its associated outcomes.
Review of pertinent English-language literature.
Race is a marker of poverty, preexisting conditions, increased allostatic loads, and decreased access to health systems. Racial disparities and the incidence of sepsis likely are explained by a multiplicity of environmental factors that are not captured by administrative data.
Race is a surrogate for many intangible factors that lead to the development of sepsis and inferior outcomes.
败血症是一种由侵袭性感染引发的过度全身炎症反应。大量流行病学文献探讨了败血症在性别和种族等人口统计学因素方面的感知差异。也有多项研究检查了败血症与环境和社会经济因素之间的差异。本文综述了当前评估种族与败血症发展及其相关结局之间关联的流行病学文献。
对相关英文文献进行回顾。
种族是贫困、既往疾病、全身压力负荷增加以及获得卫生系统机会减少的标志。种族差异和败血症的发病率可能是由行政数据无法捕捉到的多种环境因素造成的。
种族是导致败血症和较差结局的许多无形因素的替代指标。
