Department of Psychiatry, Federal University of São Paulo - Escola Paulista de Medicina - UNIFESP, São Paulo, Brazil.
Curr Opin Psychiatry. 2012 Nov;25(6):462-7. doi: 10.1097/YCO.0b013e3283578cdd.
This review highlights the key recent issues and novel findings on anxiety disorders in older adults. Studies of the epidemiology, medical and psychiatric comorbidity, neurobiology, and treatment of anxiety in the elderly are discussed.
Overall prevalence studies of anxiety symptoms or disorders in older adults indicate that, although less common than in younger adults, they are relatively common in late life. We examine the prevalence of specific anxiety disorders in the elderly, as mechanisms, outcomes, and treatment response may vary by type of anxiety disorder. Physical and psychiatric comorbidity are common. Certain anxiety disorders, such as generalized anxiety disorder, have demonstrated a positive impact following acute coronary syndrome. Regarding treatment, small effect sizes and incomplete response are typical, posing a challenge when treating this age group.
The epidemiology, neurobiology, and treatment of anxiety conditions in late life have recently received more attention in the medical literature. Areas in need of further investigation include neurobiology, clinical presentation, management, and treatment, as we do not know whether procedures indicated for younger cohorts hold for older adults.
本篇综述强调了老年人焦虑障碍方面的一些关键新问题和新发现。本文讨论了老年人焦虑症的流行病学、医学和精神共病、神经生物学以及治疗研究。
老年人焦虑症状或障碍的总体患病率研究表明,尽管不如年轻人常见,但在晚年也相对常见。我们检查了老年人特定焦虑障碍的患病率,因为不同类型的焦虑障碍的发病机制、结果和治疗反应可能不同。身体和精神共病很常见。某些焦虑症,如广泛性焦虑症,在急性冠状动脉综合征后显示出积极的影响。关于治疗,小的效应量和不完全反应是常见的,这对治疗这个年龄组构成了挑战。
近年来,医学文献中对老年人焦虑症的流行病学、神经生物学和治疗方法给予了更多的关注。需要进一步研究的领域包括神经生物学、临床表现、管理和治疗,因为我们不知道针对年轻患者的程序是否适用于老年患者。