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74岁及以上社区居住老年人的焦虑症状:与身体疾病、抑郁和饮酒的关联。

Anxiety symptoms in 74+ community-dwelling elderly: associations with physical morbidity, depression and alcohol consumption.

作者信息

Forlani Martina, Morri Monica, Belvederi Murri Martino, Bernabei Virginia, Moretti Francesca, Attili Tobias, Biondini Anna, De Ronchi Diana, Atti Anna Rita

机构信息

Department of Biomedical and NeuroMotor Sciences - Psychiatry, University of Bologna, Bologna, Italy.

Department of Neuroscience, Division of Psychiatry, University of Parma, Parma, Italy.

出版信息

PLoS One. 2014 Feb 26;9(2):e89859. doi: 10.1371/journal.pone.0089859. eCollection 2014.

Abstract

OBJECTIVE

Anxiety among community-dwelling older adults has not been studied sufficiently. The aims of this cross-sectional population-based study were to estimate the point prevalence of clinically relevant anxiety symptoms and to describe their socio-demographic and clinical features, with particular focus on the association with somatic illnesses.

METHODS

Three-hundred-sixty-six non-demented older adults (mean age 83.7±6.2, range 74-99 years) from the Faenza Project (Northern Italy) were assessed using the Cambridge Mental Disorders of the Elderly Examination-Revised (CAMDEX-R) and the Geriatric Anxiety Inventory short form (GAI-sf). Multi-adjusted regression analyses were used to estimate Odds Ratio (OR) and 95% Confidence Intervals (95% CI).

RESULTS

Clinically relevant anxiety symptoms occurred in one out of five participants (point prevalence 21.0%) and were significantly associated with depression (OR 5.6 per rank; 95% CI: 3.1-10.1), physical morbidity (OR 3.5 per illness; 95% CI: 1.0-11.9) and female gender (OR 2.8; 95% CI: 1.4-5.5). Further, there were significant associations with a consumption of alcohol exceeding 1 alcoholic unit/day.

CONCLUSIONS

Anxiety symptoms are very common in older subjects, especially when medically ill. Depression and alcohol consumption often co-occur with late-life anxiety symptoms, thus requiring special attention in daily clinical practice.

摘要

目的

针对社区居住的老年人焦虑症的研究尚不充分。本基于人群的横断面研究旨在估计具有临床意义的焦虑症状的时点患病率,并描述其社会人口学和临床特征,尤其关注与躯体疾病的关联。

方法

使用修订版的剑桥老年精神障碍检查表(CAMDEX-R)和老年焦虑量表简表(GAI-sf)对来自意大利北部法恩扎项目的366名非痴呆老年人(平均年龄83.7±6.2岁,范围74-99岁)进行评估。采用多因素调整回归分析来估计比值比(OR)和95%置信区间(95%CI)。

结果

五分之一的参与者出现了具有临床意义的焦虑症状(时点患病率21.0%),且与抑郁(每等级OR 5.6;95%CI:3.1-10.1)、躯体疾病(每种疾病OR 3.5;95%CI:1.0-11.9)和女性性别(OR 2.8;95%CI:1.4-5.5)显著相关。此外,与每天饮酒超过1个酒精单位也存在显著关联。

结论

焦虑症状在老年人群中非常常见,尤其是在患有躯体疾病时。抑郁和饮酒常常与老年焦虑症状同时出现,因此在日常临床实践中需要特别关注。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c19/3935948/7347c6a555cb/pone.0089859.g001.jpg

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