Belverud Shawn A, Mogilner Alon Y, Schulder Michael
North Shore University Hospital Department of Neurosurgery, Harvey Cushing Institute for Neuroscience, Manhasset, NY, USA.
Local Reg Anesth. 2010;3:125-8. doi: 10.2147/LRA.S7841. Epub 2010 Oct 11.
Direct central nervous system (CNS) analgesic delivery is a useful option when more traditional means of dealing with chronic pain fail. Solutions containing local anesthetic have been effective in certain disease states, particularly in patients suffering from intractable head and neck pain. This review discusses historical aspects of CNS drug delivery and the role of intrathecal bupivacaine-containing solutions in refractory head and neck pain patients.