Cuvellier J C, Gottrand F, Largillière C, Farriaux J P
Service de Pédiatrie et Génétique Médicale, Hôpital Huriez, Lille.
Ann Pediatr (Paris). 1990 Dec;37(10):669-71.
Bronze baby syndrome is an infrequent complication of phototherapy for neonatal jaundice which develops in infants with liver disease. The characteristic feature is a grayish-brown discoloration of the skin, plasma and urine. Three cases are reported. There was one case each of bile duct atresia, galactosemia, and parenteral nutrition with cholestasis. The pigment responsible for the discoloration has not been identified and pathogenesis remains unelucidated. The bronze color disappears spontaneously and the prognosis is dependent on the causative liver disease for which investigations should be performed routinely.
青铜色婴儿综合征是新生儿黄疸光疗的一种罕见并发症,发生于患有肝病的婴儿。其特征性表现为皮肤、血浆和尿液呈灰棕色变色。本文报告了3例病例。分别为胆管闭锁、半乳糖血症及伴有胆汁淤积的肠外营养各1例。导致变色的色素尚未明确,发病机制也仍不清楚。青铜色会自发消失,预后取决于引起该病的肝病,对此应常规进行检查。