Marinopoulos Spyridon, Lourantou Dionysia, Gatzionis Thomas, Dimitrakakis Constantine, Papaspyrou Irini, Antsaklis Aris
Breast Unit, 1st Obstetrics and Gynecology Department, Athens University Medical School, Alexandra Hospital, Athens, Greece.
Int J Surg Case Rep. 2012;3(11):548-50. doi: 10.1016/j.ijscr.2012.07.003. Epub 2012 Jul 20.
Mammary (breast) tuberculosis is a rare manifestation of extra-pulmonary localization of the disease which accounts for less than 0.1% of breast conditions in developed countries, but reaches 3-4% in regions where the disease presents with high incidence (India, Africa). It appears mostly in women of reproductive age, multiparous, lactating. It has been scarcely reported to infect male patients, mainly before puberty, as well as women of older age. The most common presentation is that of a tumor in the middle or upper-outer quadrant of the breast, with multifocal involvement being rarely documented. The differential diagnosis includes breast cancer and abscess formation.
We report a case of breast tuberculosis that was treated in the Breast Unit of our hospital. Differential diagnosis, imaging methods, operative diagnostic approach and surgical treatment, histological verification of the disease and further therapeutic management are described.
High risk population is identified, primary and secondary disease is described and clinical presentations are analyzed. Evaluation of diagnostic workup and limitations are reported.
In accordance with the present worldwide revival of the disease, mainly because of massive numbers of migrating population, this subject is reviewed, reminding us of a rather uncommon clinical entity.
乳腺结核是该疾病肺外定位的一种罕见表现形式,在发达国家占乳腺疾病的比例不到0.1%,但在该病高发地区(印度、非洲)可达3%-4%。它主要出现在育龄经产妇、哺乳期妇女中。极少有报道称男性患者会感染,主要是青春期前的男性以及老年女性。最常见的表现是乳腺中外象限或上外象限出现肿物,多灶性受累情况很少见。鉴别诊断包括乳腺癌和脓肿形成。
我们报告了我院乳腺科诊治的一例乳腺结核病例。描述了鉴别诊断、影像学方法、手术诊断方法和手术治疗、疾病的组织学验证以及进一步的治疗管理。
确定了高危人群,描述了原发性和继发性疾病并分析了临床表现。报告了诊断检查的评估及局限性。
鉴于目前该病在全球范围内的再度流行,主要是由于大量移民人口,对该主题进行了回顾,提醒我们这是一种相当罕见的临床实体。