手术应激和促肾上腺皮质激素对家兔甲状腺激素外周代谢的影响。
Effects of surgical stress and corticotrophin on the peripheral metabolism of thyroid hormones in rabbits.
作者信息
Ramsden D B, Smith T J, Burr W A, Black E G, Lee J M, Hoffenberg R
出版信息
J Endocrinol. 1979 Sep;82(3):403-8. doi: 10.1677/joe.0.0820403.
PMID:229182
Abstract
The effect of surgical stress and ACTH injection on the peripheral monodeiodination of thyroxine (T4) was studied in the rabbit. These stimuli resulted in a switch from the peripheral formation of tri-iodothyronine (T3) to reverse T3 in normal rabbits and in rabbits whose thyroidal secretion was suppressed by administration of T4. This is analogous to the situation in man. These changes were not due to alterations in the serum binding capacity for thyroid hormones.
摘要
在兔子身上研究了手术应激和促肾上腺皮质激素注射对甲状腺素（T4）外周单碘脱碘作用的影响。这些刺激导致正常兔子以及甲状腺分泌因给予T4而受到抑制的兔子，其外周甲状腺激素从三碘甲状腺原氨酸（T3）的生成转向反式T3的生成。这与人类的情况相似。这些变化并非由于血清甲状腺激素结合能力的改变所致。
Zotero 插件