[长春市儿童病毒性腹泻的病因及流行病学研究]
[Etiological and epidemiological study on viral diarrhea among children in Changchun].
作者信息
Zhang Xian-E, Li Dan-Di, Li Xiang, Yang Xian-Da, Cai Kun, Wang Yong-Xia, Yang Li-Bin, Duan Zhaojun
机构信息
The First Hospital of Jilin University, Changchun 130021, China.
出版信息
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2012 Feb;26(1):5-7.
OBJECTIVE
To study the pathogen and characteristics of viral diarrhea in children in Changchun area.
METHODS
460 stools specimens were collected from children with acute diarrhea cured in the childrens, hospital of Changchun in 2010. Rotavirus were detected by ELISA, caliceverus and astrovirus were detected by reverse transcription-polymerase chain reactions (RT-PCR), adenovirus were detected by polymerase chain reactions (PCR).
RESULTS
A total of 460 specimens were detected. The detection rate of rotavirus, caliceverus, astrovious, adenovious respectively is 35.22%, 20.43%, 9.78%, 3.70%, the detectablerate of mixed infection is 7.61%, children under 2 years old were the major patient. The main genotypes of the virus: rotavirus (G3P[8]), caliceverus (GII-4), astrovious (type I), adenovious (Ad41).
CONCLUSION
Rotavirus is the main pathogen in Changchun. Followed by caliceverus, astrovious, adenovious.
目的
研究长春地区儿童病毒性腹泻的病原体及特点。
方法
收集2010年在长春市儿童医院治愈的急性腹泻患儿的460份粪便标本。采用酶联免疫吸附测定法检测轮状病毒，采用逆转录-聚合酶链反应（RT-PCR）检测杯状病毒和星状病毒，采用聚合酶链反应（PCR）检测腺病毒。
结果
共检测460份标本。轮状病毒、杯状病毒、星状病毒、腺病毒的检出率分别为35.22%、20.43%、9.78%、3.70%，混合感染检出率为7.61%，2岁以下儿童为主要患病群体。病毒的主要基因型：轮状病毒（G3P[8]）、杯状病毒（GII-4）、星状病毒（I型）、腺病毒（Ad41）。
结论
轮状病毒是长春地区主要病原体。其次是杯状病毒、星状病毒、腺病毒。
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