Kuerpick Birte, Fiedor Christiane, von Samson-Himmelstjerna Georg, Schnieder Thomas, Strube Christina
Institute for Parasitology, University of Veterinary Medicine Hannover, Hannover, Germany.
Berl Munch Tierarztl Wochenschr. 2012 Jul-Aug;125(7-8):345-50.
The liver fluke Fasciola (F) hepatica is one of the most important trematodes in cattle farming worldwide. Fasciolosis in dairy cows is leading to production losses due to decreased milk yield, liver condemnation and impaired reproduction. The treatment of dairy cows is unsatisfactory, because available drugs are either effective against adult flukes only or have long withdrawal times or in some countries may not be used at all. In the present study the prevalence of F. hepatica in dairy farms located in East Frisia, which is part of the federal state Lower Saxony, was investigated. East Frisia is considered a high risk area for Fasciola hepatica infections, because of its coastal location, high precipitation and moist pastures. About 750 bulk milk samples were collected in January and November 2006 and analysed for F. hepatica antibodies using the Pourquier ELISA. In addition, questionnaires, which were answered by 260 of the participating farmers, were evaluated to analyse management-related factors associated with fasciolosis. In January and November, 52.1% and 53.6% of the bulk milk samples, respectively, showed positive results. Thereby, 88.1% of the examined farms showed an unchanged infection status, whereas 6.2% of the farms became seropositive during the grazing season and 5.8% of the dairy herds turned seronegative. Statistical analysis revealed a significant negative association between average annual milk production and the frequency of infections with F. hepatica.
肝片吸虫（Fasciola (F) hepatica）是全球养牛业中最重要的吸虫之一。奶牛的肝片吸虫病导致产奶量下降、肝脏废弃和繁殖能力受损，从而造成生产损失。奶牛的治疗效果并不理想，因为现有的药物要么仅对成虫有效，要么停药期长，或者在某些国家根本不能使用。在本研究中，对位于下萨克森州的东弗里斯兰地区的奶牛场中肝片吸虫的流行情况进行了调查。东弗里斯兰因其沿海位置、高降水量和潮湿的牧场，被认为是肝片吸虫感染的高风险地区。2006年1月和11月收集了约750份散装牛奶样本，并使用Pourquier ELISA检测肝片吸虫抗体。此外，对260名参与调查的农民回答的问卷进行了评估，以分析与肝片吸虫病相关的管理因素。1月和11月，散装牛奶样本的阳性结果分别为52.1%和53.6%。因此，88.1%的受检农场感染状况未变，而6.2%的农场在放牧季节血清呈阳性，5.8%的奶牛群血清呈阴性。统计分析显示，年平均产奶量与肝片吸虫感染频率之间存在显著的负相关。
