Coston A-L, Hoffmann P, Equy V, Sergent F, Vidal C
Service de gynécologie-obstétrique et médecine de la reproduction, hôpital Couple Enfant, université Joseph-Fourrier Grenoble 1, CHU de Grenoble, BP 217, 38043 Grenoble cedex 9, France.
Gynecol Obstet Fertil. 2012 Sep;40(9):549-52. doi: 10.1016/j.gyobfe.2012.07.004. Epub 2012 Aug 21.
We report the 2 cases of schizophrenic patients with clozapine treatment and particularly, we underlined a reduced variability and low short-term variability, whereas biophysical ultrasound score, Dopplers and perception of fetal movements were acceptable and comfortable concerning the fetal vitality. Our aim is to show the limits of the analyzed fetal heart rate under clozapine. So, we may change our observation of fetus in chronic suffering that is usually mainly made with an informatics analysis of pregnants under clozapine.
我们报告了2例接受氯氮平治疗的精神分裂症患者的情况,特别强调了其变异性降低和短期变异性低,而生物物理超声评分、多普勒检查和胎动感知在胎儿活力方面是可接受且令人满意的。我们的目的是展示氯氮平治疗下分析胎儿心率的局限性。因此,对于长期患病孕妇,我们可能会改变通常主要基于对服用氯氮平孕妇进行信息学分析的胎儿观察方式。