Dusaud M, Durand X, Lahutte M, Desfemmes F-R, Vedrine L, Houlgatte A
Service d'urologie, hôpital du Val-de-Grâce, 74, boulevard de Port-Royal, 75230 Paris cedex 05, France.
Prog Urol. 2012 Sep;22(10):568-71. doi: 10.1016/j.purol.2012.04.001. Epub 2012 May 31.
Growing teratoma syndrome (GTS) is a rare entity, characterized by enlarging masses of the retroperitoneum or other location occurring during or after systemic chemotherapy for the treatment of non-seminomatous germ cell of the testis (NSGCT). Three criteria define this syndrome: enlarging metastatic masses, normalized serum markers and no component of viable germ cell tumor in this mature teratoma. Prognostic is excellent after the resection of these masses, but this surgery has to be as much complete as possible. Surgical excision of large GTS lesions is technically challenging, a serious intraoperative complications may occur, that's why the treatment must not be delayed.
生长性畸胎瘤综合征（GTS）是一种罕见病症，其特征为在对睾丸非精原细胞生殖细胞肿瘤（NSGCT）进行全身化疗期间或之后，腹膜后或其他部位出现不断增大的肿块。该综合征由三个标准定义：转移性肿块不断增大、血清标志物恢复正常以及在这种成熟畸胎瘤中不存在活的生殖细胞肿瘤成分。切除这些肿块后的预后极佳，但这种手术必须尽可能完整。大型GTS病变的手术切除在技术上具有挑战性，可能会发生严重的术中并发症，这就是治疗不能延迟的原因。
