Department of Radiology, University of Washington, Seattle, WA, USA.
Clin Imaging. 2012 Sep-Oct;36(5):647-9. doi: 10.1016/j.clinimag.2011.11.011. Epub 2012 Jun 8.
Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare disorder that is being diagnosed more frequently with the increasing availability of advanced imaging and more accurate histopathology. It occurs most commonly in nonsmoking, middle-aged women. High-resolution computed tomography (HRCT) findings include mosaic attenuation due to constrictive bronchiolitis and small (<5 mm) randomly distributed pulmonary nodules. It is important to recognize this condition as it is considered a precursor of peripheral carcinoid tumors. This article will present a case of this uncommon condition with review of the literature, imaging findings, and clinical presentation.
弥漫特发性肺神经内分泌细胞增生症（DIPNECH）是一种罕见疾病，随着先进影像学技术的普及和更准确的组织病理学检查的应用，其诊断率逐渐增高。该病多见于不吸烟的中年女性。高分辨率计算机断层扫描（HRCT）的表现包括因缩窄性细支气管炎引起的马赛克衰减和随机分布的小结节（<5mm）。认识到这种情况很重要，因为它被认为是周围类癌肿瘤的前兆。本文将通过文献复习、影像学表现和临床表现来介绍这一罕见病例。
