甜味产生胃酸分泌过程中的胃迷走神经功能分布

Gastric vagal functional distribution in the secretion of gastric acid produced by sweet taste.

作者信息

Ikuno H, Sakaguchi T

机构信息

Department of Oral Physiology, Niigata University School of Dentistry, Japan.

出版信息

Brain Res Bull. 1990 Sep;25(3):429-31. doi: 10.1016/0361-9230(90)90233-p.

DOI:10.1016/0361-9230(90)90233-p

PMID:2292041

Abstract

The sweet signal pathway relevant to lingual control of gastric acid secretion was examined in bilaterally adrenalectomized rats. The increase in the acid output after lingual glucose application was completely blocked by prior section of both sides of the vagus nerve at the cervical level. However, the reduction in the acid output showed no laterality following vagotomy on either side. At the subdiaphragmatic level, the acid response was mainly suppressed by section of the dorsal vagus trunk. Both sides of trunk vagotomy abolished the acid response. These results suggest that the sweet signal evoking gastric acid secretion has a specific pathway from the tongue to the stomach, and that there is functional laterality in this pathway in the visceral cavity.

摘要

在双侧肾上腺切除的大鼠中研究了与胃酸分泌的舌部控制相关的甜味信号通路。舌部给予葡萄糖后胃酸分泌量的增加在双侧迷走神经于颈部水平预先切断后被完全阻断。然而，胃酸分泌量的减少在任一侧迷走神经切断后均无偏向性。在膈下水平，胃酸反应主要通过切断迷走神经背干来抑制。双侧迷走神经干切断消除了胃酸反应。这些结果表明，引发胃酸分泌的甜味信号具有从舌到胃的特定通路，并且在体腔内该通路存在功能偏向性。