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腹腔镜孕前腹扎术:一项多中心队列研究。

Preconceptional laparoscopic abdominal cerclage: a multicenter cohort study.

机构信息

Department of Obstetrics and Gynecology, VU University Medical Center, Amsterdam, the Netherlands.

出版信息

Am J Obstet Gynecol. 2012 Oct;207(4):273.e1-12. doi: 10.1016/j.ajog.2012.07.030. Epub 2012 Jul 27.

Abstract

OBJECTIVE

The purpose of this study was to evaluate the effectiveness of laparoscopic abdominal cerclage placement in the prevention of recurrent preterm birth.

STUDY DESIGN

We conducted a multicenter cohort study with retrospective Dutch (32 patients) and Boston (34 patients) cohorts who had undergone preconceptional laparoscopic abdominal cerclage placement. Eligible patients had at least 1 second/third trimester fetal loss or delivered at <34 weeks of gestation because of cervical insufficiency and/or a short or absent cervix. Primary outcome was delivery of an infant at ≥ 34 weeks of gestation with neonatal survival. Secondary outcome measures included surgical and pregnancy outcomes and patients' satisfaction (Dutch cohort).

RESULTS

Surgical outcomes of 66 patients were excellent, with 3 minor complications. After preconceptional laparoscopic abdominal cerclage, 35 pregnancies were evaluated. Twenty-five patients (71.4%) delivered at ≥ 34 weeks of gestation; 3 patients (8.6%) experienced a second-trimester fetal loss. The total fetal survival rate was 90.0%.

CONCLUSION

Preconceptional laparoscopic abdominal cerclage shows encouraging and favorable perinatal outcomes in patients with a poor obstetric history.

摘要

目的

本研究旨在评估腹腔镜腹部环扎术预防复发性早产的有效性。

研究设计

我们进行了一项多中心队列研究,纳入了接受孕前腹腔镜腹部环扎术的荷兰(32 例患者)和波士顿(34 例患者)队列。符合条件的患者至少有 1 次/3 次中期胎儿丢失或因宫颈机能不全和/或宫颈短或缺失而在 34 周前分娩。主要结局是≥34 周分娩并新生儿存活。次要结局指标包括手术和妊娠结局以及患者满意度(荷兰队列)。

结果

66 例患者的手术结果良好,仅有 3 例轻微并发症。在孕前腹腔镜腹部环扎术后,对 35 例妊娠进行了评估。25 例患者(71.4%)≥34 周分娩;3 例患者(8.6%)发生中期胎儿丢失。总的胎儿存活率为 90.0%。

结论

对于产科病史不佳的患者,孕前腹腔镜腹部环扎术显示出令人鼓舞的良好围产结局。

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