Department of Obstetrics and Gynecology, VU University Medical Center, Amsterdam, the Netherlands.
Am J Obstet Gynecol. 2012 Oct;207(4):273.e1-12. doi: 10.1016/j.ajog.2012.07.030. Epub 2012 Jul 27.
The purpose of this study was to evaluate the effectiveness of laparoscopic abdominal cerclage placement in the prevention of recurrent preterm birth.
We conducted a multicenter cohort study with retrospective Dutch (32 patients) and Boston (34 patients) cohorts who had undergone preconceptional laparoscopic abdominal cerclage placement. Eligible patients had at least 1 second/third trimester fetal loss or delivered at <34 weeks of gestation because of cervical insufficiency and/or a short or absent cervix. Primary outcome was delivery of an infant at ≥ 34 weeks of gestation with neonatal survival. Secondary outcome measures included surgical and pregnancy outcomes and patients' satisfaction (Dutch cohort).
Surgical outcomes of 66 patients were excellent, with 3 minor complications. After preconceptional laparoscopic abdominal cerclage, 35 pregnancies were evaluated. Twenty-five patients (71.4%) delivered at ≥ 34 weeks of gestation; 3 patients (8.6%) experienced a second-trimester fetal loss. The total fetal survival rate was 90.0%.
Preconceptional laparoscopic abdominal cerclage shows encouraging and favorable perinatal outcomes in patients with a poor obstetric history.
本研究旨在评估腹腔镜腹部环扎术预防复发性早产的有效性。
我们进行了一项多中心队列研究,纳入了接受孕前腹腔镜腹部环扎术的荷兰(32 例患者)和波士顿(34 例患者)队列。符合条件的患者至少有 1 次/3 次中期胎儿丢失或因宫颈机能不全和/或宫颈短或缺失而在 34 周前分娩。主要结局是≥34 周分娩并新生儿存活。次要结局指标包括手术和妊娠结局以及患者满意度(荷兰队列)。
66 例患者的手术结果良好,仅有 3 例轻微并发症。在孕前腹腔镜腹部环扎术后,对 35 例妊娠进行了评估。25 例患者(71.4%)≥34 周分娩;3 例患者(8.6%)发生中期胎儿丢失。总的胎儿存活率为 90.0%。
对于产科病史不佳的患者,孕前腹腔镜腹部环扎术显示出令人鼓舞的良好围产结局。