University of Maryland, Baltimore County, Department of Psychology, 1000 Hilltop Circle, Baltimore, MD 21250, USA.
Schizophr Res. 2012 Oct;141(1):72-7. doi: 10.1016/j.schres.2012.07.022. Epub 2012 Aug 22.
Brief self-report questionnaires that assess attenuated psychosis symptoms have the potential to quickly and effectively screen many people who may benefit from clinical monitoring or early intervention. The current study sought to examine and compare the criterion validities of attenuated symptoms screening tools with diagnoses obtained from the clinician-administered Structured Interview for Psychosis Risk Syndromes (SIPS). Three screening questionnaires (Prime Screen, Prodromal Questionnaire-Brief, and Youth Psychosis At-Risk Questionnaire-Brief) were administered just prior to the SIPS interview in a sample of adolescents and young adults seeking mental health services. Using thresholds recommended by instrument authors as well as empirically derived optimal thresholds, the sensitivity, specificity, positive predictive value, and overall accuracy of each self-report measure with regard to SIPS diagnosis were obtained. Screeners correlated highly with the SIPS and demonstrated equivalent overall efficiency in capturing psychosis risk status. All three screeners appear to be useful and valid assessment tools for attenuated symptoms, with each instrument demonstrating relative benefits. The validation of attenuated symptoms screening tools is an important step toward enabling early, wide-reaching identification of individuals on a course toward psychotic illness.
简短的自我报告问卷可以评估减轻的精神病症状，有可能快速有效地筛选出许多可能受益于临床监测或早期干预的人群。本研究旨在检查和比较衰减症状筛查工具与临床医生管理的精神病风险综合征结构化访谈 (SIPS) 获得的诊断之间的标准效度。在寻求心理健康服务的青少年和年轻人样本中，在进行 SIPS 访谈之前，使用了三种筛查问卷（Prime Screen、前驱症状问卷-简短版和青年精神病风险问卷-简短版）。使用仪器作者推荐的阈值以及经验得出的最佳阈值，获得了每个自我报告量表相对于 SIPS 诊断的灵敏度、特异性、阳性预测值和总体准确性。筛查器与 SIPS 高度相关，在捕捉精神病风险状态方面具有同等的整体效率。这三种筛查器似乎都是有用且有效的衰减症状评估工具，每种工具都有相对的优势。衰减症状筛查工具的验证是实现对精神病发病过程中的个体进行早期、广泛识别的重要步骤。
