Jacobs A, Lenoir P, Delree M, Ramet J, Piepsz A
Department of Nuclear Medicine, Academic Hospital, Vrije Universiteit, Brussel, Belgium.
Clin Nucl Med. 1990 Nov;15(11):821-4. doi: 10.1097/00003072-199011000-00013.
A 6-year-old boy presented with an inflammatory syndrome. Because Tc-99m MDP bone scintigraphy revealed increased tracer uptake at the upper pole of the right kidney, further studies were oriented towards a diagnosis of renal or adrenal pathology. I-123 metaiodobenzylguanidine (MIBG) accumulated at the site of the abnormal MDP uptake. The diagnosis of neuroblastoma or allied disorder was excluded on the basis of other investigations and further evaluation, suggesting that the MIBG uptake was a false-positive. Findings on clinical imaging, laboratory findings, Tc-99m DMSA imaging, sonography, and CT scanning were highly suggestive of acute focal pyelonephritis.
一名6岁男孩出现炎症综合征。由于锝-99m亚甲基二膦酸盐(Tc-99m MDP)骨闪烁显像显示右肾上极示踪剂摄取增加,进一步检查旨在诊断肾脏或肾上腺病变。碘-123间碘苄胍(I-123 MIBG)在异常MDP摄取部位聚集。根据其他检查和进一步评估排除了神经母细胞瘤或相关疾病的诊断,提示MIBG摄取为假阳性。临床影像学、实验室检查结果、Tc-99m二巯基丁二酸(Tc-99m DMSA)显像、超声检查和CT扫描结果高度提示急性局灶性肾盂肾炎。