Division of Pediatric Surgery and Urology, Servidores do Estado Federal Hospital, Ministry of Health, Rio de Janeiro, Brazil.
Urology. 2012 Oct;80(4):919-21. doi: 10.1016/j.urology.2012.06.051. Epub 2012 Aug 22.
Stevens-Johnson syndrome frequently affects the genitalia. Vaginal problems have been recognized in female patients; however, reports about the problem and its treatment are rare. Labial sinechiae have not yet been reported as sequelae of Stevens-Johnson syndrome. Amenorrhea, cyclical abdominal pain, and a hypogastric mass in girls affected by Stevens-Johnson syndrome could indicate acquired vaginal obstruction. Extensive labial sinechiae in such patients can cause dysuria, urinary tract infection, and sexual dysfunction. After a diagnosis of Stevens-Johnson syndrome in girls, it is prudent to schedule a prepubertal genital examination to diagnose genital disease preemptively and avoid obstructed menstruation and future sexual problems.
史蒂文斯-约翰逊综合征常影响生殖器。已认识到女性患者存在阴道问题；然而，关于该问题及其治疗的报告却很少。阴唇粘连尚未被报道为史蒂文斯-约翰逊综合征的后遗症。患有史蒂文斯-约翰逊综合征的女孩出现闭经、周期性腹痛和下腹肿块，可能表明阴道后天性梗阻。此类患者广泛的阴唇粘连可引起排尿困难、尿路感染和性功能障碍。在女孩被诊断为史蒂文斯-约翰逊综合征后，谨慎的做法是安排青春期前的生殖器检查，以便提前诊断生殖器疾病，避免月经阻塞和未来的性问题。
