Department of Restorative Dentistry and Prosthodontics, The University of Texas School of Dentistry, Houston, TX, USA.
J Dent. 2012 Dec;40 Suppl 2:e17-24. doi: 10.1016/j.jdent.2012.08.009. Epub 2012 Aug 23.
To evaluate clinical effectiveness, color rebound and sensitivity of 22% carbamide peroxide (CP) with 3% potassium nitrate.
Twenty-one participants were enrolled and treated overnight for 2 weeks with 22% CP (Venus White, Heraeus Kulzer). Visual color measurement was performed and expressed in shade guide units (SGU) of Vita Classical (VC) and Vita Bleachedguide 3D Master (BG) shade guides. Instrumental color measurements were performed using an intraoral spectrophotometer (Vita Easyshade Compact, EC). Color measurements were taken on a canine and central incisor at baseline, 2, 3, and 4 weeks. Participants documented sensitivity and data were analysed with Wilcoxon and Bonferroni correction at the 0.05 level of significance.
Mean BG SGU difference immediately, 1 and 2 weeks postbleaching compared to baseline was 4.9 (2.1), 4.5 (2.2) and 4.6 (2.0), respectively. Corresponding VC values were 7.0 (3.5), 6.4 (3.3) and 6.5 (3.4), while corresponding ΔE* values were 8.3 (4.1), 8.1 (4.0) and 7.9 (3.5). For visual shade evaluation there was a significant decrease in SGU from baseline and each subsequent week, p<0.001. There was no difference between week 3 and week 4 using VC or BG. For instrumental color measurements, there was no difference from week 2 to week 3 for canines and generally no difference between week 3 and week 4 for incisors.
Visual and instrumental evaluation showed rebound occurred 1 week postbleaching with 22% carbamide peroxide and 3% potassium nitrate. In general, color was stable at 2 weeks postbleaching. Participants reported low sensitivity levels with a mean value of below 2 on a 0-10 scale.
This study demonstrates efficacy with overnight usage of 22% carbamide peroxide with 3% potassium nitrate and demonstrates postbleaching color is stable at two weeks with low tooth sensitivity.
评估 22%过氧化脲（CP）与 3%硝酸钾的临床效果、颜色反弹和敏感度。
纳入 21 名参与者，使用 22%CP（维纳斯白，贺利氏古莎）进行 2 周的夜间治疗。进行视觉颜色测量，并以 Vita Classical（VC）和 Vita Bleachedguide 3D Master（BG）比色指南的比色单位（SGU）表示。使用口腔内分光光度计（Vita Easyshade Compact，EC）进行仪器颜色测量。在基线、第 2、3 和 4 周时，在犬齿和中切牙上进行颜色测量。参与者记录敏感度，数据以 Wilcoxon 和 Bonferroni 校正进行分析，显著性水平为 0.05。
与基线相比，即刻、漂白后 1 周和 2 周时 BG SGU 差值分别为 4.9（2.1）、4.5（2.2）和 4.6（2.0）。相应的 VC 值分别为 7.0（3.5）、6.4（3.3）和 6.5（3.4），而相应的ΔE*值分别为 8.3（4.1）、8.1（4.0）和 7.9（3.5）。对于视觉比色评估，从基线到后续每一周，SGU 均显著降低，p<0.001。使用 VC 或 BG 时，第 3 周与第 4 周之间无差异。对于仪器颜色测量，犬齿在第 2 周到第 3 周之间没有差异，中切牙在第 3 周到第 4 周之间通常没有差异。
视觉和仪器评估显示，使用 22%过氧化脲和 3%硝酸钾漂白后 1 周出现反弹。一般来说，漂白后 2 周颜色稳定。参与者报告的敏感度平均值低于 2，在 0-10 刻度上。
本研究表明，使用 22%过氧化脲和 3%硝酸钾进行 1 晚治疗具有疗效，并表明漂白后 2 周颜色稳定，牙齿敏感度低。
