Department of Restorative Dentistry, Dental School, Federal University of Pará, Belém, Pará, Brazil.
Clin Exp Dent Res. 2024 Feb;10(1):e817. doi: 10.1002/cre2.817.
This study assessed whether combining photobiomodulation therapy (PBMT) with casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF) paste can effectively reduce post-home whitening tooth sensitivity (TS) without compromising shade change.
Fifty participants were selected and assigned to one of four groups: (1) PLACEBO group-received a placebo paste and PBMT simulation; (2) PBMT group-received a placebo paste + PBMT; (3) CPP-ACPF group-received CPP-ACPF paste and PBMT simulation; (4) CPP-ACPF + PBMT group-received both CPP-ACPF paste and PBMT. The participants used whitening trays containing 22% carbamide peroxide for 2 h a day for 21 days. TS was measured daily using a visual analog scale, while shade change was assessed using a spectrophotometer: before bleaching treatment (T0), after the first (T1), second (T2), and third (T3) weeks of treatment, and 30 days (T4) after completing the whitening treatment.
Intragroup analysis revealed that the PLACEBO group had the highest increase in sensitivity during the whitening treatment. The CPP-ACPF and PBMT groups showed no significant difference tooth whitening (TW) between weeks regarding aesthetic change. The CPP-ACPF and PBMT group exhibited a significant reduction in TS between the first and third and between the second and third weeks TW, but not between the first and second. Conversely, the PLACEBO group showed a higher sensitivity than the other groups (p < .05). The CPP-ACPF and PBMT groups did not differ from each other. Furthermore, the CPP-ACPF and PBMT group showed a greater decrease in sensitivity than the PLACEBO group at T1, T2, and T3 (p < .01), and was significantly differed from CPP-ACPF and PBMT groups only at T2 and T3. All groups confirmed TW effectiveness. Student's and paired t-test did not reveal any significant difference between groups (p > .05).
Therefore, PBMT associated with CPP-ACPF paste can reduce TS without compromising the efficacy of TW.
本研究旨在评估光生物调节疗法(PBMT)联合酪蛋白磷酸肽-无定形磷酸钙氟化物(CPP-ACPF)糊剂是否可以在不影响牙齿美白效果的情况下有效减轻家庭美白后牙齿敏感(TS)。
选择 50 名参与者,并将其分为四组:(1)安慰剂组-接受安慰剂糊剂和 PBMT 模拟治疗;(2)PBMT 组-接受安慰剂糊剂+PBMT;(3)CPP-ACPF 组-接受 CPP-ACPF 糊剂和 PBMT 模拟治疗;(4)CPP-ACPF+PBMT 组-接受 CPP-ACPF 糊剂和 PBMT。参与者使用含有 22%过氧脲的美白托盘,每天使用 2 小时,持续 21 天。每日使用视觉模拟量表测量 TS,同时使用分光光度计评估颜色变化:在漂白治疗前(T0)、第一次(T1)、第二次(T2)和第三次(T3)周治疗后以及完成美白治疗后 30 天(T4)。
组内分析显示,安慰剂组在美白治疗过程中敏感性增加最高。CPP-ACPF 和 PBMT 组在各周的 TW 期间,在美观变化方面没有显著差异。CPP-ACPF 和 PBMT 组在第一周和第三周以及第二周和第三周的 TW 期间,TS 显著降低,但在第一周和第二周之间没有差异。相反,安慰剂组的敏感性高于其他组(p<.05)。CPP-ACPF 和 PBMT 组之间没有差异。此外,CPP-ACPF 和 PBMT 组在 T1、T2 和 T3 时的敏感性降低比安慰剂组更大(p<.01),仅在 T2 和 T3 时与 CPP-ACPF 和 PBMT 组有显著差异。所有组均证实了 TW 的有效性。学生和配对 t 检验显示组间无显著差异(p>.05)。
因此,CPP-ACPF 糊剂联合 PBMT 可以减轻 TS,同时不影响 TW 的疗效。