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新型 CPP-ACP 改性过氧化物自酸蚀家庭美白技术的疗效及其对牙釉质显微硬度的影响。

Efficacy of a novel at-home bleaching technique with carbamide peroxides modified by CPP-ACP and its effect on the microhardness of bleached enamel.

机构信息

Department of Restorative Dentistry, University of Pernambuco, Camaragibe, Pernambuco, Brazil.

出版信息

Oper Dent. 2011 Sep-Oct;36(5):521-8. doi: 10.2341/11-013-L. Epub 2011 Aug 5.

DOI:10.2341/11-013-L
PMID:21819199
Abstract

This study was designed to evaluate in vitro the efficacy of a novel at-home bleaching technique using 10% or 16% carbamide peroxide modified by casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and its influence on the microhardness of bleached enamel. A total of 40 bovine incisors were divided into four groups (n=10) according to the bleaching agent used: 10% carbamide peroxide only; a blend of 10% carbamide peroxide and a CPP-ACP paste; 16% carbamide peroxide only; and a blend of 16% carbamide peroxide and a CPP-ACP paste. During the 14-day bleaching regimen, the samples were stored in artificial saliva. The Vickers microhardness and color of the teeth were assessed at baseline (T0) and immediately after the bleaching regimen (T14) using a microhardness tester and a spectrophotometer, respectively. The degree of color change was determined by the Commission Internationale de l'Eclariage (CIE) Lab* system (ΔE, ΔL*, Δa*, and Δb*) and Vita shade guide parameters. The data were analyzed by analysis of variance and the Tukey test (p<0.05). The teeth that were bleached with a blend of peroxide (10% or 16%) and the CPP-ACP paste presented increased microhardness values at T14 compared with T0, whereas the samples that were bleached with peroxide only did not show any differences in their microhardness values. All of the bleaching agents were effective at whitening the teeth and did not show a statistically significant difference using the CIELab* system (ΔE, ΔL*, Δa*, and Δb*) or the Vita shade guide parameters. The use of a CPP-ACP paste with carbamide peroxide bleaching agents increased the bleached enamel's microhardness and did not have an influence on whitening efficacy.

摘要

本研究旨在评估一种新型的家庭用漂白技术,该技术使用 10%或 16%的过氧脲,通过酪蛋白磷酸肽-无定形磷酸钙(CPP-ACP)进行修饰,及其对漂白牙釉质的显微硬度的影响。根据所用的漂白剂,将 40 颗牛切牙分为四组(n=10):仅使用 10%的过氧脲;10%过氧脲与 CPP-ACP 糊剂的混合物;仅使用 16%过氧脲;以及 16%过氧脲与 CPP-ACP 糊剂的混合物。在 14 天的漂白疗程中,样本被储存在人工唾液中。使用显微硬度计和分光光度计,分别在基线(T0)和漂白疗程结束后即刻(T14)评估牙齿的维氏显微硬度和颜色。颜色变化程度通过国际照明委员会(CIE)Lab系统(ΔE、ΔL、Δa和Δb)和 Vita 比色指南参数来确定。数据采用方差分析和 Tukey 检验进行分析(p<0.05)。与 T0 相比,用过氧化物(10%或 16%)和 CPP-ACP 糊剂混合漂白的牙齿在 T14 时显微硬度值增加,而只用过氧化物漂白的样本在其显微硬度值上没有差异。所有的漂白剂都能有效美白牙齿,使用 CIELab系统(ΔE、ΔL、Δa和Δb)或 Vita 比色指南参数没有显示出统计学上的显著差异。在过氧脲漂白剂中使用 CPP-ACP 糊剂可以提高漂白牙釉质的显微硬度,并且对美白效果没有影响。

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