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终生骨折报告:方法学考量及泰国队列研究结果

Reporting of lifetime fractures: methodological considerations and results from the Thai Cohort Study.

作者信息

Berecki-Gisolf Janneke, McClure Rod, Seubsman Sam-Ang, Sleigh Adrian

机构信息

Monash Injury Research Institute, Monash University, Melbourne, Australia.

出版信息

BMJ Open. 2012 Aug 24;2(4). doi: 10.1136/bmjopen-2012-001000. Print 2012.

Abstract

OBJECTIVES

To provide estimates of fracture incidence among young adults in Thailand.

DESIGN

Cross-sectional analysis of a large national cohort.

SETTING

Thailand.

PARTICIPANTS

A total of 60 569 study participants residing nationwide responded to the 2009 follow-up survey; 55% were women and median age was 34 years (range 19-92).

OUTCOME MEASURES

Self-reported lifetime fractures, along with age at fracture. Fracture incidence rates per person-year were then compared using lifetime fracture reports, and again selecting only fractures reported for the last year. Incidence rates were compared by age and sex.

RESULTS

18 010 lifetime fractures were reported; 11 645(65%) by men. Lifetime fracture prevalence was 30% for men and 15% for women. Lifetime incidence per 10 000 person-years was 83; analysing only fractures from the last year yielded a corresponding incidence rate of 187. For ages 21-30, fractures per 10 000 person-years were more common among men than women (283 (95% CI 244 to 326) and 150 (130 to 173), respectively); with increasing age, rates decreased among men and increased among women (for ages 51-60, 97 (58 to 151) and 286 (189 to 417), respectively).

CONCLUSIONS

Large-scale surveys provide a feasible method for establishing relative fracture incidence among informative subgroups in a population. Limiting analyses to fractures reported to have occurred recently minimises bias due to poor recall. The pattern of self-reported fracture incidence among Thais aged 20-60 was similar to that reported for Western countries: high falling rates in young men and high rising rates in older women.

摘要

目的

估算泰国年轻人的骨折发病率。

设计

对一个大型全国队列进行横断面分析。

地点

泰国。

参与者

全国共有60569名研究参与者回应了2009年的随访调查;55%为女性,中位年龄为34岁(范围19 - 92岁)。

观察指标

自我报告的终生骨折情况以及骨折时的年龄。然后使用终生骨折报告比较每人每年的骨折发病率,再次仅选择报告的过去一年发生的骨折。发病率按年龄和性别进行比较。

结果

报告了18010例终生骨折;男性报告了11645例(65%)。男性终生骨折患病率为30%,女性为15%。每10000人年的终生发病率为83;仅分析过去一年的骨折得出相应发病率为187。对于21 - 30岁年龄组,每10000人年的骨折在男性中比女性更常见(分别为283(95%可信区间244至326)和150(130至173));随着年龄增长,男性发病率下降,女性发病率上升(对于51 - 60岁年龄组,分别为97(58至151)和286(189至417))。

结论

大规模调查为确定人群中有信息价值的亚组间相对骨折发病率提供了一种可行方法。将分析限于报告为近期发生的骨折可最大程度减少因回忆不佳导致的偏倚。20 - 60岁泰国人自我报告的骨折发病率模式与西方国家报告的相似:年轻男性摔倒率高,老年女性上升率高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c23/3433778/da61f46a496e/bmjopen2012001000f01.jpg

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