Endocrinology and Metabolism Research Institute of Tehran University of Medical Sciences, Tehran, Iran.
Department of Medicine, Section of Endocrinology, Nutrition, and Diabetes, Vitamin D, Skin and Bone Research Laboratory, Boston University Medical Campus, Boston, Massachusetts, USA
BMJ Open. 2017 Apr 11;7(4):e014898. doi: 10.1136/bmjopen-2016-014898.
It is estimated that Iran accounted for about 1% of hip fracture burden of the world in 2007, but these data are based on incomplete evidence. As the country's population is ageing, it is expected that a dramatic rise in hip fracture incidence will result. There is no single national study that accurately estimates the incidence of all hip fractures in the country or identifies the direct costs for affected patients. To help fill this gap, the current study has been designed to determine the incidence of hip fracture associated with osteoporosis in the Iranian population and to assess the direct costs involved.
This is a cross-sectional analysis of 2 years of hospital admissions due to hip fracture in Iran from October 2014 to October 2016 using an electronic health record called SEPAS. SEPAS is a nationwide health information system established by Information Technology (IT) and the Statistics Department of the Ministry of Health. SEPAS has recorded more than 8.5 million inpatient hospitalizations since October 2014. Our study will identify reported hip fracture data in SEPAS among admitted adult hospital patients aged ≥50 in Iran. International Classification of Diseases ICD-9 and 10 will be used as diagnostic codes. Study factors are demographic data, types of fracture, types of treatment, duration of admission, early complications, in-hospital mortality and direct cost of fracture treatment. The accuracy of the SEPAS fracture data will be ascertained through a pilot study that compares the SEPAS data with the data directly extracted from medical records of the Shariati Hospital in Tehran during the study period.
The study protocol was approved by the Ethics Committee of the National Institute for Medical Research Development of Iran. Dissemination plans include academic publications, conference presentations and social media.
据估计，2007 年伊朗约占全球髋部骨折负担的 1%，但这些数据基于不完整的证据。随着国家人口老龄化，髋部骨折发病率预计将大幅上升。目前还没有一项全国性的研究能够准确估计该国所有髋部骨折的发病率，也无法确定患者的直接费用。为了帮助填补这一空白，本研究旨在确定伊朗骨质疏松性髋部骨折的发病率，并评估相关的直接费用。
这是对 2014 年 10 月至 2016 年 10 月伊朗因髋部骨折住院的 2 年的医院入院情况进行的横断面分析，使用名为 SEPAS 的电子健康记录。SEPAS 是由信息技术 (IT) 和卫生部统计部门建立的全国性健康信息系统。自 2014 年 10 月以来，SEPAS 已记录了超过 850 万例住院患者。我们的研究将在 SEPAS 中确定报告的髋部骨折数据，这些数据来自伊朗年龄≥50 岁的住院成年患者。国际疾病分类 ICD-9 和 10 将被用作诊断代码。研究因素包括人口统计学数据、骨折类型、治疗类型、住院时间、早期并发症、住院死亡率和骨折治疗的直接费用。通过试点研究来确定 SEPAS 骨折数据的准确性，该研究将 SEPAS 数据与研究期间直接从德黑兰 Shariati 医院病历中提取的数据进行比较。
该研究方案已获得伊朗国家医学研究发展研究所伦理委员会的批准。传播计划包括学术出版物、会议演讲和社交媒体。
