中国新型 H9N2 亚型流感病毒 FJG9 株的全基因组序列揭示了一次自然重配事件。
Complete genome sequence of a novel H9N2 subtype influenza virus FJG9 strain in China reveals a natural reassortant event.
机构信息
College of Animal Science, South China Agricultural University, Tianhe District, Wushan Road, Guangzhou, Guangdong, People's Republic of China.
出版信息
J Virol. 2012 Sep;86(18):10240-1. doi: 10.1128/JVI.01623-12.
Abstract
A/chicken/FJ/G9/09 (FJ/G9) is an H9N2 subtype avian influenza virus (H9N2 AIV) strain causing high morbidity that was isolated from broilers in Fujian Province of China in 2009. FJ/G9 has been used as the vaccine strain against H9N2 AIV infection in Fujian Province of China. Here, we report the complete genome sequence of FJ/G9 with natural six-way reassortment, which is the most complex genotype strain in China and even in the world so far. The present findings will aid in understanding the complexity and diversity of H9N2 subtype avian influenza virus.
摘要
A/chicken/FJ/G9/09（FJ/G9）是一株分离自 2009 年中国福建省肉鸡的 H9N2 亚型禽流感病毒（H9N2 AIV），其具有高发病率的特点。FJ/G9 已被用作中国福建省针对 H9N2 AIV 感染的疫苗株。在此，我们报道了 FJ/G9 的全基因组序列，其具有天然的六重基因重配，是目前为止中国甚至全球最为复杂的基因型毒株。本研究结果将有助于理解 H9N2 亚型禽流感病毒的复杂性和多样性。
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