Halimi Monireh, Aghbali Amirala, Emamverdizadeh Parya, Talesh Koroush Taheri
Department of Pathology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
J Oral Maxillofac Pathol. 2012 May;16(2):291-3. doi: 10.4103/0973-029X.99093.
The inverted papilloma is a unilateral sinonasal benign tumor which is characterized by aggressive local invasion, high recurrence rate, and transformation into malignancy. The etiology of inverted papilloma is still unknown. Possible causes include allergy, chronic sinusitis, occupational exposure to dusts and aerosols, tobacco, and viral infections. Treatment is complete surgical excision and close postoperative follow-up is necessary. Here we report a case of inverted papilloma arising from the hard palate with malignant transformation in a 41-year-old female. Clinical and histological features and treatment are discussed with the review of literature.
内翻性乳头状瘤是一种单侧鼻窦良性肿瘤，其特点是局部侵袭性强、复发率高以及恶变。内翻性乳头状瘤的病因仍不清楚。可能的病因包括过敏、慢性鼻窦炎、职业性接触粉尘和气溶胶、烟草以及病毒感染。治疗方法是彻底手术切除，术后密切随访是必要的。在此，我们报告一例41岁女性硬腭来源的内翻性乳头状瘤伴恶变的病例。结合文献复习讨论了其临床和组织学特征及治疗方法。
