Cancer Control Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA.
Health Serv Res. 2013 Apr;48(2 Pt 1):628-51. doi: 10.1111/j.1475-6773.2012.01456.x. Epub 2012 Aug 27.
To estimate the effect of breastfeeding duration on childhood obesity.
The Child Development Supplement (CDS) of the Panel Study of Income Dynamics (PSID). The PSID provides extensive data on the income and well-being of a representative sample of U.S. families from 1968 to the present. The CDS collects information on the children in PSID families ranging from cognitive, behavioral, and health status to their family and neighborhood environment. The first two waves of the CDS were conducted in 1997 and 2002, respectively. The data provide information on 3,271 children and their mothers.
We use the generalized propensity score to adjust for confounding based on continuous treatment, and the general additive model to analyze the adjusted association between treatment and the outcome conditional on the propensity score. The main outcome is the body mass index (BMI) directly assessed during the in-person interview in 2002. Covariates include family, maternal, and child characteristics, many of which were measured in the year the child was born.
After using propensity scores to adjust for confounding, the relationship between breastfeeding duration and childhood BMI is trivially small across a range of model specifications, and none of them is statistically significant except the unadjusted model.
The causal link between duration of breastfeeding and childhood obesity has not been established. Any recommendation of promoting breastfeeding to reduce childhood obesity is premature.
评估母乳喂养持续时间对儿童肥胖的影响。
收入动态面板研究(PSID)的儿童发展补充(CDS)。PSID 提供了从 1968 年至今美国代表性家庭的收入和福利的广泛数据。CDS 收集了 PSID 家庭中儿童的信息,包括认知、行为和健康状况以及他们的家庭和社区环境。CDS 的前两个波次分别于 1997 年和 2002 年进行。该数据提供了 3271 名儿童及其母亲的信息。
我们使用广义倾向评分来调整基于连续治疗的混杂因素,并使用广义加性模型来分析调整后的治疗与倾向评分条件下的结果之间的关联。主要结果是 2002 年面对面访谈中直接评估的体重指数(BMI)。协变量包括家庭、母亲和儿童特征,其中许多特征是在孩子出生当年测量的。
在使用倾向评分调整混杂因素后,母乳喂养持续时间与儿童 BMI 之间的关系在一系列模型规范中微不足道,除了未调整的模型外,没有一个模型具有统计学意义。
母乳喂养持续时间与儿童肥胖之间的因果关系尚未确立。任何提倡母乳喂养以减少儿童肥胖的建议都是不成熟的。