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手术挑战:脑脊液漏的内镜修复

Surgical challenge: endoscopic repair of cerebrospinal fluid leak.

作者信息

Martín-Martín Carlos, Martínez-Capoccioni Gabriel, Serramito-García Ramón, Espinosa-Restrepo Federico

机构信息

Servizo Galego de Saúde, Service of ENT–Head and Neck Surgery, University Hospital Complex of Santiago de Compostela (CHUS), Santiago de Compostela, Spain.

出版信息

BMC Res Notes. 2012 Aug 27;5:459. doi: 10.1186/1756-0500-5-459.

Abstract

BACKGROUND

Cerebrospinal fluid leaks (CSF) result from an abnormal communication between the subarachnoid space and the extracranial space. Approximately 90% of CSF leak at the anterior skull base manifests as rhinorrhea and can become life-threatening condition. Endoscopic sinus surgery (ESS) has become a common otolaryngologist procedure. The aim of this article is to consider our experience and to evaluate the outcomes in patients who underwent a purely endoscopic repair of CSF leaks of the anterior skull base.

FINDINGS

Retrospective chart review was performed of all patients surgically treated for CSF leaks presenting to the Section of Nasal and Sinus Disorders at the Service of ENT-Head and Neck Surgery, University Hospital Complex of Santiago de Compostela (CHUS), between 2004 and 2010. A total of 30 patients who underwent repair CSF leak by ESS. The success rate was 93.4% at the first attempt; only two patients (6.6%) required a second surgical procedure, and none of it was necessary to use a craniotomy for closure. Follow-up periods ranged from 4 months to 6 years.

CONCLUSION

Identifying the size, site, and etiology of the CSF leak remains the most important factor in the surgical success. It is generally accepted that the ESS have made procedures minimally invasive, and CSF leak is now one of its well-established indications with low morbidity and high success rate, with one restriction for fistulas of the posterior wall of the frontal sinus should be repaired in conjunction with open techniques.

摘要

背景

脑脊液漏是由于蛛网膜下腔与颅外空间之间的异常连通所致。前颅底脑脊液漏约90%表现为鼻漏,可成为危及生命的状况。内镜鼻窦手术(ESS)已成为耳鼻喉科医生常用的手术。本文旨在介绍我们的经验,并评估接受前颅底脑脊液漏单纯内镜修复的患者的治疗效果。

研究结果

对2004年至2010年间在圣地亚哥德孔波斯特拉大学医院综合体(CHUS)耳鼻喉头颈外科鼻及鼻窦疾病科接受手术治疗的所有脑脊液漏患者进行回顾性病历审查。共有30例患者接受了ESS修复脑脊液漏。首次尝试的成功率为93.4%;只有两名患者(6.6%)需要进行第二次手术,且均无需开颅手术进行闭合。随访时间为4个月至6年。

结论

确定脑脊液漏的大小、部位和病因仍然是手术成功的最重要因素。人们普遍认为,ESS使手术微创化,脑脊液漏现在是其成熟的适应症之一,发病率低且成功率高,但额窦后壁瘘的修复应结合开放技术进行。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b9/3438049/b391b91514a5/1756-0500-5-459-1.jpg

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