Arshad Muhammad, Faisal Malik Jawad, Ashfaq Ahmed Hasan, Riaz Nida, Maqbool Shahzaib
Department of otorhinolaryngology and head and neck surgery, Benazir Bhutto Hospital, Rawalpindi, Pakistan.
Department of ENT, Pakistan institute of medical sciences (PIMS), Islamabad, Pakistan.
Indian J Otolaryngol Head Neck Surg. 2024 Feb;76(1):748-752. doi: 10.1007/s12070-023-04267-2. Epub 2023 Oct 13.
Cerebrospinal Fluid (CSF) rhinorrhea results from breakdown in the integrity of structures separating the subarachnoid space and nasal cavity, namely subarachnoid space and dura mater, the bony skull base and periostea alongside the upper aerodigestive tract mucosa. Endoscopic repair is considered the treatment of choice for CSF rhinorrhea. Our aim of study was to analyze the etiopathogenesis and outcomes of treatment.
A retrospective study review of patients treated with endoscopic repair of CSF rhinorrhea at tertiary care hospital in ENT Department Benazir Bhutto hospital Rawalpindi from august 2013 to September 2017 identified 25 patients. Majority of them were male. The defects were closed in three layers using fat, fascia lata and nasal mucosa along with fibrin sealant in majority of patients. Pre operatively subarachnoid drain was placed in all patients. Patients were followed up to 3 months.
Forty-four patients underwent endoscopic repair of CSF rhinorrhea. The age group ranged from 16 to 55 years. Of the total of 44 patients 26 (59%) were males and 18(41%) females. The mean age of the patients in our study was 32.8 ± 9.7. Post trauma CSF leak was seen up to 52.3% of the patients. The most common site of leakage was identified Cribriform plate area. Our success rate of endoscopic repair was 88.6%. The most commonly observed complication was meningitis that was observed in 2 (4.5%) of the patients that too were managed conservatively.
Accurate localization of site of leakage appears to be essential for successful endoscopic repair of CSF rhinorrhea. In our study cribriform plate area was commonly observed area of CSF leak. In our study, the success rate was 88.6% and low complication rate 4.5%.
脑脊液鼻漏是由于蛛网膜下腔与鼻腔之间结构的完整性遭到破坏所致,这些结构包括蛛网膜下腔和硬脑膜、颅骨基底以及上呼吸道消化道黏膜旁的骨膜。内镜修复被认为是脑脊液鼻漏的首选治疗方法。我们的研究目的是分析其病因发病机制及治疗结果。
对2013年8月至2017年9月在拉瓦尔品第贝娜齐尔·布托医院耳鼻喉科三级护理医院接受内镜修复脑脊液鼻漏治疗的患者进行回顾性研究,共确定25例患者。其中大多数为男性。大多数患者使用脂肪、阔筋膜和鼻黏膜分三层封闭缺损,并使用纤维蛋白密封剂。所有患者术前均放置蛛网膜下腔引流管。对患者进行了3个月的随访。
44例患者接受了脑脊液鼻漏的内镜修复。年龄范围为16至55岁。在44例患者中,26例(59%)为男性,18例(41%)为女性。我们研究中患者的平均年龄为32.8±9.7岁。高达52.3%的患者出现创伤后脑脊液漏。最常见的漏出部位是筛板区域。我们的内镜修复成功率为88.6%。最常见的并发症是脑膜炎,2例(4.5%)患者出现该并发症,且均经保守治疗。
准确确定漏出部位似乎是脑脊液鼻漏内镜修复成功的关键。在我们的研究中,筛板区域是常见的脑脊液漏出区域。在我们的研究中,成功率为88.6%,并发症发生率低至4.5%。