Joint BioEnergy Institute, Feedstocks Division, Emeryville, CA 94608, USA.
Trends Plant Sci. 2013 Jan;18(1):49-58. doi: 10.1016/j.tplants.2012.07.002. Epub 2012 Aug 25.
The plant cell wall mostly comprises complex glycans, which are synthesized by numerous enzymes located in the Golgi apparatus and plasma membrane. Protein-protein interactions have been shown to constitute an important organizing principle for glycan biosynthetic enzymes in mammals and yeast. Recent genetic and biochemical data also indicate that such interactions could be common in plant cell wall biosynthesis. In this review, we examine the new findings in protein-protein interactions among plant cell wall biosynthetic enzymes and discuss the possibilities for enzyme complexes in the Golgi apparatus. These new insights in the field may contribute to novel strategies for molecular engineering of the cell wall.
植物细胞壁主要由复杂的聚糖组成，这些聚糖是由位于高尔基体和质膜中的许多酶合成的。已经表明，蛋白质-蛋白质相互作用是哺乳动物和酵母中糖生物合成酶的一个重要组织原则。最近的遗传和生化数据也表明，这种相互作用在植物细胞壁生物合成中可能很常见。在这篇综述中，我们检查了植物细胞壁生物合成酶之间蛋白质-蛋白质相互作用的新发现，并讨论了在高尔基体中形成酶复合物的可能性。该领域的这些新见解可能有助于细胞壁的分子工程的新策略。
