Key Laboratory of Ecology Model and Applications of State Ethnic Affairs Commission, College of Biology Sciences and Engineering, Beifang University of Nationalities, Yinchuan 750021, Ningxia, China.
J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2012 Nov;198(11):787-96. doi: 10.1007/s00359-012-0748-8. Epub 2012 Aug 29.
Although early paternal deprivation significantly affects offspring behavioral and neuroendocrine development, the link between paternal deprivation and social play behavior remains unclear. Mandarin voles (Microtus mandarinus) are socially monogamous and display bi-paternal care. The present study examined the development of social play in juvenile male mandarin voles and the paternal influence on play-fighting, vasopressin- and oxytocin-immunoreactive neurons and serum corticosterone and testosterone levels. The results show that social play was more pronounced during postnatal days 28-35, differing from the ontogenetic pattern of other forms of social behavior. On postnatal day 35, the peak in play-fighting activity, paternal deprivation reduced boxing/wrestling levels and vasopressin-immunoreactive neurons in the anterior hypothalamus and oxytocin-immunoreactive neurons in the paraventricular nucleus, but increased vasopressin-immunoreactive neurons in the paraventricular nucleus and corticosterone levels. These results suggest that mandarin voles engage in social play according to an inverted U-shaped curve in ontogeny, and paternal deprivation influences the development of offspring play-fighting; hypothalamic vasopressin, oxytocin and serum corticosterone may play a modulatory role in the alteration of play-fighting elicited by paternal deprivation; decreased play-fighting may correlate with depressed vasopressin levels in the anterior hypothalamus.
虽然早期的父爱剥夺会显著影响后代的行为和神经内分泌发育，但父爱剥夺与社交玩耍行为之间的联系尚不清楚。布氏田鼠（Microtus mandarinus）是社会性一夫一妻制的，并且表现出双亲照顾。本研究检查了幼年雄性布氏田鼠社交玩耍的发展以及父爱对玩耍打斗、加压素和催产素免疫反应神经元以及血清皮质酮和睾酮水平的影响。结果表明，社交玩耍在出生后第 28-35 天更为明显，与其他形式的社交行为的发生模式不同。在第 35 天，玩耍打斗活动达到高峰，父爱剥夺降低了拳击/摔跤水平以及前下丘脑的加压素免疫反应神经元和室旁核的催产素免疫反应神经元，但增加了室旁核的加压素免疫反应神经元和皮质酮水平。这些结果表明，布氏田鼠根据发育的倒 U 形曲线进行社交玩耍，父爱剥夺会影响后代玩耍打斗的发育；下丘脑加压素、催产素和血清皮质酮可能在父爱剥夺引起的玩耍打斗改变中发挥调节作用；玩耍打斗减少可能与前下丘脑加压素水平降低有关。
