Raman Siva P, Singhi Aatur, Horton Karen M, Hruban Ralph H, Fishman Elliot K
Department of Radiology, Johns Hopkins University School of Medicine, JHOC 3251, 601 N. Caroline Street, Baltimore, MD 21287, USA.
Abdom Imaging. 2013 Aug;38(4):827-34. doi: 10.1007/s00261-012-9949-4.
Sclerosing angiomatoid nodular transformation (SANT) is an extremely rare splenic lesion first reported in 2004, representing an unusual reaction of splenic red pulp to stromal inflammation or vascular injury. There are very few descriptions of the imaging appearance of SANT in the literature. We present five pathologically proven cases of SANT, with a description of the imaging appearance using multiple different modalities, as well as correlation with the histopathologic features of the lesion.
While there are several imaging features of SANT which have been described in the literature, it is not routinely possible to make a prospective diagnosis based on the imaging features alone. Moreover, it may not be possible to exclude malignancy based on the imaging features, and splenectomy may be required in certain cases.
硬化性血管瘤样结节性转化（SANT）是一种极为罕见的脾脏病变，于2004年首次报道，代表脾红髓对间质炎症或血管损伤的一种异常反应。文献中对SANT的影像学表现描述极少。我们展示5例经病理证实的SANT病例，描述其使用多种不同检查方式的影像学表现，以及与病变组织病理学特征的相关性。
虽然文献中已描述了SANT的几种影像学特征，但仅根据影像学特征常规进行前瞻性诊断是不可能的。此外，根据影像学特征可能无法排除恶性肿瘤，在某些情况下可能需要进行脾切除术。
