Van den Eede Sander, Van de Voorde Nick, Vanhoenacker Filip, Op de Beeck Bart
University of Antwerp, BE.
Antwerp University Hospital and Antwerp University, Edegem, Belgium, BE.
J Belg Soc Radiol. 2022 Apr 5;106(1):12. doi: 10.5334/jbsr.2689. eCollection 2022.
A splenic lesion often represents a diagnostic challenge due to relative scarcity and the broad differential diagnosis. Sclerosing Angiomatoid Nodular Transformation (SANT) of the spleen is usually encountered only incidentally. Although benign, patients with SANT often receive splenectomy, due to its rarity, diagnostic uncertainty and sometimes intimidating imaging morphology and size. Imaging features on computed tomography, magnetic resonance and positron emission tomography have a high diagnostic value for SANT and help differentiate this entity from other splenic lesions. When the imaging parameters are matched with core needle biopsy tissue analysis, further watchful waiting can be recommended in order to avoid splenectomy.
由于相对少见且鉴别诊断范围广，脾脏病变常常带来诊断挑战。脾脏硬化性血管瘤样结节性转化（SANT）通常只是偶然发现。尽管SANT是良性病变，但由于其罕见性、诊断不确定性以及有时令人担忧的影像学形态和大小，患有SANT的患者常接受脾切除术。计算机断层扫描、磁共振成像和正电子发射断层扫描的影像学特征对SANT具有较高的诊断价值，并有助于将该病变与其他脾脏病变区分开来。当影像学参数与粗针活检组织分析结果相符时，可以建议进一步密切观察，以避免行脾切除术。
