CAF-603：一种新型抗真菌类胡萝卜烷倍半萜。分离与结构解析。
CAF-603: a new antifungal carotane sesquiterpene. Isolation and structure elucidation.
作者信息
Watanabe N, Yamagishi M, Mizutani T, Kondoh H, Omura S, Hanada K, Kushida K
机构信息
Research Institute, Taisho Pharmaceutical, Saitama-ken, Japan.
出版信息
J Nat Prod. 1990 Sep-Oct;53(5):1176-81. doi: 10.1021/np50071a006.
PMID:2292685
Abstract
A new antifungal compound, CAF-603, was isolated from the culture broth of Gliocladium virens IFO 9166. The structure of compound 1 has been elucidated by spectroscopic methods that also allowed the relative stereochemistry to be assigned. CAF-603 [1] was active against yeasts and dermatophytes.
摘要
一种新型抗真菌化合物CAF-603从绿粘帚霉IFO 9166的培养液中分离得到。化合物1的结构已通过光谱方法阐明，该方法还可确定其相对立体化学结构。CAF-603 [1]对酵母和皮肤癣菌具有活性。
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