丘疹霉素，一类具有抗真菌活性的新型抗生素，I. 丘疹霉素A、B、C、D和E的发酵、分离、化学及生物学特性
Papulacandins, a new family of antibiotics with antifungal activity, I. Fermentation, isolation, chemical and biological characterization of papulacandins A, B, C, D and E.
作者信息
Traxler P, Gruner J, Auden J A
出版信息
J Antibiot (Tokyo). 1977 Apr;30(4):289-96. doi: 10.7164/antibiotics.30.289.
PMID:324958
Abstract
Papulacandin, a new antibiotic complex, active against Candida albicans and several other yeasts, was isolated from a strain of Papularia sphaerosperma. The fermentation, isolation, physico-chemical properties and biological activity of the five structurally related papulacandins A, B, C, D and E are reported. Papulacandin B, the main component, was assigned the formula of C47H64O17.
摘要
丘疹霉素是一种新型抗生素复合物，对白色念珠菌和其他几种酵母具有活性，它是从球形丘疹菌菌株中分离得到的。本文报道了五种结构相关的丘疹霉素A、B、C、D和E的发酵、分离、理化性质及生物活性。主要成分丘疹霉素B的分子式为C47H64O17。
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