对墨西哥传统药用植物的化学研究，十五。来自光叶希藤的倍半萜埃沃宁酸酯生物碱。

Chemical studies on Mexican plants used in traditional medicine, XV. Sesquiterpene evoninoate alkaloids from Hippocratea excelsa.

作者信息

Mata R, Calzada F, Díaz E, Toscano R A

机构信息

División de Bioquímica y Farmacia, Facultad de Química, Ciudad Universitaria, México D.F.

出版信息

J Nat Prod. 1990 Sep-Oct;53(5):1212-9. doi: 10.1021/np50071a012.

DOI:10.1021/np50071a012

PMID:2292687

Abstract

Three sesquiterpene evoninoate alkaloids, hippocrateine I [1], hippocrateine II [2], and emarginatine A have been isolated from the root and stem barks of Hippocratea excelsa. Compounds 1 and 2 are new naturally occurring substances. The structure of 1 was unequivocally established by X-ray crystallographic analysis, and the structure of the second new alkaloid was deduced by spectral analysis.

摘要

从光叶希藤的根皮和茎皮中分离出了三种倍半萜烯埃沃宁酸酯生物碱，即希藤碱I [1]、希藤碱II [2]和边缘藤碱A。化合物1和2是新的天然产物。通过X射线晶体学分析明确确定了1的结构，通过光谱分析推断出了第二种新生物碱的结构。