Huang Sha, Fu Xiaobing
Int J Burns Trauma. 2011;1(1):1-10. Epub 2011 Aug 25.
During the past few years, tissue-engineered skin constructs has offered great promise in the treatment of deep burns and various skin-related disorders. The overall impact of bioengineered skin research, as a multidisciplinary field, has also enhanced our understanding of the structure-function relations and the physiological processes of tissue regeneration within these constructed three-dimensional skin models. Despite of the fact that currently available bioengineered skin products have a range of problems such as patient safety, clinical efficacy and convenience of use, they are still one of the most advanced strategies because of their wide use and potential development in the biomedical field. Here, the challenges and developments in tissue-engineered skin research are discussed. Central to the discussion is the extensive application and future prospects of these bioengineered skin constructs.
在过去几年中，组织工程皮肤构建物在深度烧伤和各种皮肤相关疾病的治疗中展现出了巨大的前景。作为一个多学科领域，生物工程皮肤研究的整体影响也加深了我们对这些构建的三维皮肤模型中结构 - 功能关系以及组织再生生理过程的理解。尽管目前可用的生物工程皮肤产品存在一系列问题，如患者安全性、临床疗效和使用便利性等，但由于它们在生物医学领域的广泛应用和潜在发展，仍然是最先进的策略之一。在此，讨论了组织工程皮肤研究中的挑战与进展。讨论的核心是这些生物工程皮肤构建物的广泛应用和未来前景。
