Saltzman Bryan M, Bajaj Sarvottam, Salata Michael, Daley Erika L, Strauss Eric, Verma Nikhil, Cole Brian J
Division of Sports Medicine, Department of Orthopedics, Rush University Medical Center, Chicago, Illinois 60612, USA.
J Knee Surg. 2012 May;25(2):165-75. doi: 10.1055/s-0032-1313738.
This study reports the long-term effectiveness of meniscal allograft transplantation performed by a single senior operating surgeon. In this study 22 meniscus transplantations in 22 patients were evaluated at a minimum of 7-year follow-up (mean 8.5 +/- 1.3 years) using standardized scoring scales. Subgroup analysis was performed to stratify outcomes based on medial (59.1%) versus lateral (40.9%) meniscus transplantation, and transplantations performed in isolation (36.4%) versus those performed concomitantly (63.6%). Patients reported significant improvement in all scoring scales (p < 0.05). Average satisfaction was 8.8 out of 10. All the patients were completely or mostly satisfied with the results of their surgery. Overall subjective knee condition improved from 3.5 to 6.9 (p < 0.05). Patients undergoing medial compartment repair and combined transplantations reported greater improvement from baseline to followup than did their counterparts. An overall success rate of 88% was found for all patients at the final follow-up. Based on this data, meniscal allograft transplantation is a viable treatment option for meniscal-deficient patients in reducing pain, increasing range of motion, and improving patient function and satisfaction at a minimum of 7 years postsurgery.
本研究报告了由一位资深外科医生进行的半月板同种异体移植的长期疗效。在本研究中，对22例患者的22次半月板移植进行了评估，采用标准化评分量表进行至少7年的随访（平均8.5±1.3年）。进行亚组分析，根据内侧半月板移植（59.1%）与外侧半月板移植（40.9%），以及单独进行的移植（36.4%）与同时进行的移植（63.6%）对结果进行分层。患者在所有评分量表上均有显著改善（p<0.05）。平均满意度为8.8分（满分10分）。所有患者对手术结果完全或基本满意。总体主观膝关节状况从3.5改善到6.9（p<0.05）。接受内侧间室修复和联合移植的患者从基线到随访的改善程度比其他患者更大。在最后随访时，所有患者的总体成功率为88%。基于这些数据，半月板同种异体移植是半月板缺损患者的一种可行治疗选择，可在术后至少7年内减轻疼痛、增加活动范围、改善患者功能和满意度。
