Dante G, Pedrielli G, Annessi E, Facchinetti F
Mother-Infant Department, University of Modena and Reggio Emilia, Italy.
J Matern Fetal Neonatal Med. 2013 Feb;26(3):306-12. doi: 10.3109/14767058.2012.722732. Epub 2012 Oct 24.
The use of herbal remedies has been documented both among various patient groups and in the general population to promote health. The aim of this systematic review is to analyze the benefits of herb use during pregnancy.
A systematic literature search covering the period from January 1990 to September 2010 was performed using various electronic databases. Randomized controlled clinical trials (RCTs) were included. Paper quality was evaluated using the Jadad scale.
Of the 511 articles identified, 14 RCTs were eligible. Ginger was the most investigated remedy and was consistently reported to ameliorate nausea and vomiting during pregnancy better than placebo; its efficacy in doing so was noted to be equal to that of vitamin B6 and dimenhydrinate. A single trial also supported the use of Hypericum perforatum for wound healing. Cranberry, however, was not efficacious in the treatment of urinary tract infections; finally, raspberry leaf did not shorten the first stage of labor, and garlic did not prevent pre-eclampsia.
Despite the widespread, popular use of herbal remedies during pregnancy, too few studies have been devoted to specific clinical investigations. With the exception of ginger, there is no data to support the use of any other herbal supplement during pregnancy.
草药疗法在各类患者群体以及普通人群中均有记载用于促进健康。本系统评价的目的是分析孕期使用草药的益处。
利用各种电子数据库对1990年1月至2010年9月期间的文献进行系统检索。纳入随机对照临床试验（RCT）。采用雅达量表评估论文质量。
在检索到的511篇文章中，有14项RCT符合要求。生姜是研究最多的草药，一直有报道称其在缓解孕期恶心和呕吐方面比安慰剂更有效；其在这方面的疗效被认为与维生素B6和茶苯海明相当。一项试验还支持使用金丝桃属植物进行伤口愈合。然而，蔓越莓对治疗尿路感染无效；最后，覆盆子叶并未缩短第一产程，大蒜也未能预防先兆子痫。
尽管孕期广泛且普遍使用草药疗法，但针对具体临床研究的报道过少。除生姜外，尚无数据支持孕期使用任何其他草药补充剂。
