Rendle D I, Armstrong S K, Hughes K J
School of Animal and Veterinary Sciences, Charles Sturt University, Wagga Wagga, New South Wales, Australia.
Aust Vet J. 2012 Sep;90(9):358-62. doi: 10.1111/j.1751-0813.2012.00962.x. Epub 2012 Jul 27.
This report documents the treatment of a case of chronic pleuropneumonia in a 3-year-old Thoroughbred gelding. A recombinant tissue plasminogen activator (tenecteplase) and a recombinant deoxyribonucleic acidase (alphadornase) were infused into the pleural cavity as adjunctive therapy in the early stages of treatment. Instillation of fibrinolytic drugs was associated with a subjective reduction in the amount of fibrin deposition and decreased fluid accumulation within the pleural cavities. Fibrinolytic therapy may be a useful adjunctive therapy in selected cases of intrapleural disease in horses.
本报告记录了一匹3岁纯种马慢性胸膜肺炎病例的治疗情况。在治疗早期，将重组组织型纤溶酶原激活剂（替奈普酶）和重组脱氧核糖核酸酶（阿法链道酶）注入胸腔作为辅助治疗。纤维蛋白溶解药物的滴注与纤维蛋白沉积量的主观减少以及胸腔内液体蓄积的减少有关。纤维蛋白溶解疗法可能是马匹胸膜内疾病特定病例中一种有用的辅助疗法。
