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[紫外线照射兔眼后视网膜电图W波振幅的变化]

[Changes in the W-wave amplitude of the electroretinogram in rabbits after irradiation of the eyes with ultraviolet rays].

作者信息

Belousov V V

出版信息

Kosm Biol Aviakosm Med. 1990 Nov-Dec;24(6):49-51.

PMID:2292873
Abstract

Changes in W-wave amplitudes of rabbit electroretinograms (ERG) were investigated at different time intervals after eye ultraviolet irradiation with biologically effective doses, i.e. 10,000; 5,000; 3,000 and 1,000 J/m2. As compared to the controls, at early post-irradiation stages (days 2-7) the ERG W-wave amplitude decreased and at the end of the observation period (days 20-30) the parameter increased but never returned to the baseline level. The ERG W-wave amplitude remained lowered even when clinical signs of photokeratoconjunctivitis disappeared. This reduction may be a cumulative result of poor transparency of eye structures and possible changes of the retina.

摘要

研究了家兔眼在接受生物有效剂量(即10000、5000、3000和1000 J/m²)的紫外线照射后不同时间间隔的视网膜电图(ERG)W波振幅变化。与对照组相比,照射后早期阶段(第2 - 7天)ERG的W波振幅降低,而在观察期结束时(第20 - 30天)该参数升高,但从未恢复到基线水平。即使光性角膜结膜炎的临床症状消失,ERG的W波振幅仍保持降低。这种降低可能是眼结构透明度降低和视网膜可能发生变化的累积结果。

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