Department of Medicine, St Joseph's Healthcare, McMaster University, 50 Charlton Avenue East, Hamilton, Ontario L8N4A6, Canada.
Clin Chest Med. 2012 Sep;33(3):445-57. doi: 10.1016/j.ccm.2012.05.003. Epub 2012 Jul 7.
Asthma has been described as a chronic disease of the airways characterized by variable airflow obstruction, airway hyperresponsiveness, and airway inflammation. This review discusses the diagnosis and phenotyping of asthma, with a special emphasis on phenotyping based on the nature of cellular inflammation and radiological imaging and how this could be used to direct the treatment of asthma and, in the future, to apply specifically directed therapies to specific phenotypes.
哮喘被描述为一种气道的慢性疾病，其特征是可变的气流阻塞、气道高反应性和气道炎症。这篇综述讨论了哮喘的诊断和表型，特别强调了基于细胞炎症和影像学特征的表型，并探讨了如何将其用于指导哮喘的治疗，以及在未来将特定的靶向治疗应用于特定的表型。
