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香叶天竺葵油对金黄色葡萄球菌临床株的抗菌活性。

Antimicrobial activity of geranium oil against clinical strains of Staphylococcus aureus.

机构信息

Medical and Sanitary Microbiology Department, Medical University of Lodz, Hallera Sq. 1, Lodz 90-647, Poland.

出版信息

Molecules. 2012 Aug 28;17(9):10276-91. doi: 10.3390/molecules170910276.

Abstract

The aim of this work was to investigate the antibacterial properties of geranium oil obtained from Pelargonium graveolens Ait. (family Geraniaceae), against one standard S. aureus strain ATCC 433000 and seventy clinical S. aureus strains. The agar dilution method was used for assessment of bacterial growth inhibition at various concentrations of geranium oil. Susceptibility testing of the clinical strains to antibiotics was carried out using the disk-diffusion and E-test methods. The results of our experiment showed that the oil from P. graveolens has strong activity against all of the clinical S. aureus isolates-including multidrug resistant strains, MRSA strains and MLS(B)-positive strains-exhibiting MIC values of 0.25-2.50 μL/mL.

摘要

本研究旨在探讨香叶天竺葵(天竺葵科)中提取的天竺葵精油的抗菌性能,以评估其对标准金黄色葡萄球菌菌株 ATCC 433000 和 70 株临床分离金黄色葡萄球菌的抑制作用。采用琼脂稀释法评估不同浓度的天竺葵精油对细菌生长的抑制作用。采用纸片扩散法和 E 试验法对临床分离株进行抗生素药敏试验。实验结果表明,从香叶天竺葵中提取的精油对所有临床分离的金黄色葡萄球菌均具有较强的活性,包括多重耐药菌株、耐甲氧西林金黄色葡萄球菌(MRSA)菌株和 MLS(B)阳性菌株,其 MIC 值为 0.25-2.50 μL/mL。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc5a/6268326/5d13c735aa25/molecules-17-10276-g001.jpg

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