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登革热的负担:巴西茹迪亚伊——2010年1月

The burden of dengue: Jundiaí, Brazil - January 2010.

作者信息

Arenas Christian Julián Villabona, Botelho Ana Vitoria, Botelho Andrea Cristina, Passos Saulo Duarte, Zanotto Paolo Marinho de Andrade

机构信息

Laboratory of Molecular Evolution and Bioinformatics, Department of Microbiology, Biomedical Sciences Institute, Universidade de São Paulo, Brazil.

出版信息

Rev Assoc Med Bras (1992). 2012 Jul-Aug;58(4):477-80.

PMID:22930028
Abstract

OBJECTIVE

To study the antibody prevalence against dengue in the municipality of Jundiaí, São Paulo, Brazil, due to the low number of official confirmed autochthonous cases.

METHODS

A serological study on dengue infection was conducted during January 2010 and previous reports on dengue and entomological surveillance during that period were reviewed.

RESULTS

A prevalence of 7.8% IgG positive (68:876) was found. Furthermore, based on the detection of IgM antibodies in five samples, it was observed that the incidence of dengue in the city at the time of the survey contrasts with the absence of notifications by local health authorities over the same period of time.

CONCLUSION

These results highlight the discrepancies between the actual and the detected number of dengue infections, possibly due to significant numbers of asymptomatic infections aggravated by difficulties with dengue clinical diagnosis.

摘要

目的

由于官方确认的本地登革热病例数量较少,研究巴西圣保罗州容迪亚伊市登革热抗体流行情况。

方法

2010年1月开展了一项关于登革热感染的血清学研究,并回顾了该时期之前关于登革热的报告及昆虫学监测情况。

结果

发现IgG阳性率为7.8%(68/876)。此外,基于在五个样本中检测到IgM抗体,观察到调查时该市登革热发病率与同期当地卫生当局未报告病例的情况形成对比。

结论

这些结果凸显了登革热感染实际数量与检测数量之间的差异,这可能是由于大量无症状感染以及登革热临床诊断困难所致。

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