Göbel H, Klostermann H, Lindner V, Schenkl S
Abteilung Neurologie der Universität Kiel.
Neurochirurgia (Stuttg). 1990 Oct;33 Suppl 1:4-7. doi: 10.1055/s-2008-1053585.
We used transcranial Doppler ultrasonography to investigate whether a change in hemodynamics in the major arteries of the brain base occurred after diagnostic lumbar puncture. On the day before diagnostic lumbar puncture the flow in the right and left middle cerebral artery was measured in 36 patients using transcranial Doppler ultrasonography. 48 hours after lumbar puncture a second ultrasound examination was performed. We found that only patients with post-lumbar puncture headache (PLPS) showed a significant reduction in the flow of the right middle cerebral artery (p less than or equal to .05). These findings support the puncture-hole-seepage theory as pathogenetic principle of PLPS.
我们使用经颅多普勒超声检查来研究诊断性腰椎穿刺后脑基底大动脉的血流动力学是否发生变化。在诊断性腰椎穿刺前一天，使用经颅多普勒超声检查测量了36例患者左右大脑中动脉的血流。腰椎穿刺48小时后进行了第二次超声检查。我们发现，只有腰椎穿刺后头痛（PLPS）患者的右大脑中动脉血流显著减少（p≤0.05）。这些发现支持穿刺孔渗漏理论作为PLPS的发病机制。
