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燕麦在乳糜泻饮食治疗中的安全性。

The safety of oats in the dietary treatment of coeliac disease.

机构信息

Department of Nutrition and Dietetics, Royal Liverpool University Hospital, Liverpool L7 8XP, UK.

出版信息

Proc Nutr Soc. 2012 Nov;71(4):534-7. doi: 10.1017/S0029665112000791. Epub 2012 Aug 29.

DOI:10.1017/S0029665112000791
PMID:22931789
Abstract

Coeliac disease is a permanent inflammatory disorder of the small bowel affecting approximately 1% of the population. The only effective treatment that exists is exclusion of gluten from the diet. The present paper aims to review the literature as to whether oats are safe to eat for people with coeliac disease. Much data exist on the restrictive nature that adhering to a gluten-free diet imposes on an individual. If oats could be eaten, this would help reduce the restrictive nature of the diet. This in turn could lead to an increase in the quality of life. Oats are of high-nutritional value, providing a rich source of fibre, vitamins and minerals. The fibre source contains soluble fibre which is believed to help reduce LDL-cholesterol. A systematic review of the literature was conducted. Earlier studies conducted are difficult to compare as they used different methodologies and it is not known whether samples of oats in the studies were contaminated with gluten from other cereals. Many studies reviewed do not state the strain of oat used. Recent research has suggested that it may only be in certain strains of oats which could produce a toxic response to people with coeliac disease. In conclusion, research suggests that the risk from consuming oats may be less harmful than first thought; however, may vary according to the strain of oat. Handling that risk in clinical practice remains controversial.

摘要

乳糜泻是一种影响大约 1%人群的小肠的永久性炎症性疾病。目前唯一有效的治疗方法是从饮食中排除麸质。本文旨在综述有关燕麦是否对乳糜泻患者安全食用的文献。大量数据表明,坚持无麸质饮食对个人有严格的限制。如果可以食用燕麦,这将有助于减少饮食的限制。这反过来又可以提高生活质量。燕麦具有很高的营养价值,提供了丰富的纤维、维生素和矿物质来源。纤维来源含有可溶性纤维,被认为有助于降低 LDL 胆固醇。对文献进行了系统综述。早期进行的研究难以比较,因为它们使用了不同的方法,而且不知道研究中燕麦样本是否受到来自其他谷物的麸质污染。许多综述研究并未说明所用燕麦的品种。最近的研究表明,可能只有在某些燕麦品种中,才会对乳糜泻患者产生毒性反应。总之,研究表明,食用燕麦的风险可能比最初想象的要小;然而,根据燕麦的品种而有所不同。在临床实践中处理这种风险仍然存在争议。

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引用本文的文献

1
Celiac Dietary Adherence Test and Standardized Dietician Evaluation in Assessment of Adherence to a Gluten-Free Diet in Patients with Celiac Disease.乳糜泻饮食依从性测试和标准化营养师评估在评估乳糜泻患者对无麸质饮食的依从性中的作用。
Nutrients. 2020 Jul 31;12(8):2300. doi: 10.3390/nu12082300.
2
Perspective: Gluten-Free Products for Patients with Celiac Disease Should Not Contain Trace Levels.观点:患有乳糜泻的患者食用的无麸质产品不应含有微量麸质。
Adv Nutr. 2017 May 15;8(3):409-411. doi: 10.3945/an.116.014472. Print 2017 May.
3
Celiac Disease and Gluten-Free Oats: A Canadian Position Based on a Literature Review.
乳糜泻与无麸质燕麦:基于文献回顾的加拿大立场
Can J Gastroenterol Hepatol. 2016;2016:1870305. doi: 10.1155/2016/1870305. Epub 2016 Feb 24.
4
Pure Oats as Part of the Canadian Gluten-Free Diet in Celiac Disease: The Need to Revisit the Issue.纯燕麦作为乳糜泻加拿大无麸质饮食的一部分:有必要重新考虑这个问题。
Can J Gastroenterol Hepatol. 2016;2016:1576360. doi: 10.1155/2016/1576360. Epub 2016 Apr 14.