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多种躯体症状可预测功能性躯体综合征患者的健康状况受损。

Multiple somatic symptoms predict impaired health status in functional somatic syndromes.

机构信息

School of Community Based Medicine, University of Manchester, Oxford Road, Manchester, UK.

出版信息

Int J Behav Med. 2013 Jun;20(2):194-205. doi: 10.1007/s12529-012-9257-y.

Abstract

BACKGROUND

The relationship between functional somatic syndromes and multiple somatic symptoms is unclear.

PURPOSE

We assessed whether the number of somatic symptoms is a predictor of health status in three functional somatic syndromes (FSS).

METHODS

In a population-based study of 990 UK adults we assessed chronic widespread pain (CWP), chronic fatigue (CF) and irritable bowel syndrome (IBS) by questionnaire and medical record data. We assessed health status (Short Form 12 and EQ-5D), number of somatic symptoms (Somatic Symptom Inventory) and anxiety/depression (Hospital Anxiety and Depression Scale) both at baseline and at follow-up 1 year later.

RESULTS

The proportion of people with an FSS who also have multiple somatic symptoms (52-55 %) was similar in the three functional syndromes. The presence of multiple somatic symptoms was associated with more impaired health status both at baseline and at follow-up. This finding was not explained by severity of FSS. In the absence of multiple somatic symptoms, the health status of the FSS was fair or good. In multiple regression analysis, the number of somatic symptoms, the presence of a functional syndrome (CWP or CF) and anxiety/depression were predictors of EQ-5D thermometer at follow-up after adjustment for confounders.

CONCLUSIONS

Multiple somatic symptoms in people with an FSS are associated with impaired health status and this cannot be explained by more severe functional syndrome or the presence of anxiety and depression.

摘要

背景

功能性躯体综合征与多种躯体症状之间的关系尚不清楚。

目的

我们评估了躯体症状的数量是否是三种功能性躯体综合征(FSS)健康状况的预测指标。

方法

在一项针对 990 名英国成年人的基于人群的研究中,我们通过问卷调查和医疗记录数据评估了慢性广泛性疼痛(CWP)、慢性疲劳(CF)和肠易激综合征(IBS)。我们在基线和 1 年后的随访时评估了健康状况(SF-12 和 EQ-5D)、躯体症状数量(躯体症状清单)和焦虑/抑郁(医院焦虑和抑郁量表)。

结果

在三种功能性综合征中,患有 FSS 且同时存在多种躯体症状的人(52-55%)的比例相似。在基线和随访时,存在多种躯体症状与更严重的健康状况受损相关。这一发现不能用 FSS 的严重程度来解释。在没有多种躯体症状的情况下,FSS 的健康状况良好或一般。在多元回归分析中,在调整了混杂因素后,躯体症状数量、功能性综合征(CWP 或 CF)的存在以及焦虑/抑郁是 EQ-5D 温度计在随访时的预测指标。

结论

在患有 FSS 的人群中,多种躯体症状与健康状况受损相关,而这不能用更严重的功能性综合征或焦虑和抑郁的存在来解释。

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