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蛛网膜下腔出血出院后功能恢复的轨迹。

Trajectory of functional recovery after hospital discharge for subarachnoid hemorrhage.

机构信息

Department of Neurology and Neuroscience, Weill Cornell Medical College, 525 East 68th Street, New York, NY, USA.

出版信息

Neurocrit Care. 2012 Dec;17(3):343-7. doi: 10.1007/s12028-012-9772-3.

DOI:10.1007/s12028-012-9772-3
PMID:22932992
Abstract

BACKGROUND

Although there are extensive data on long-term disability after subarachnoid hemorrhage (SAH), there are few data on the trajectory of functional recovery after hospital discharge.

METHODS

From October 2009 to April 2010, we prospectively followed consecutive patients with non-traumatic SAH discharged from a university hospital. Modified Rankin Scale (mRS) scores were calculated at discharge from chart review and at 6 months by standardized telephone interview. Good functional status was defined as a mRS score of 0-2, and poor status as an mRS score of 3-6. Descriptive statistics were used to assess the trajectory of functional recovery and determine the proportion of patients whose functional status improved from poor to good.

RESULTS

Among 52 patients with non-traumatic SAH (79 % aneurysmal) who were discharged alive, most (71 %) were discharged home. Median (IQR) mRS score was 3 (2-4) at discharge and 2 (1-2) at 6 months. Some functional recovery (any improvement in mRS score) was seen in most patients (83 %; 95 % CI, 72-93 %). Of the 28 patients with poor functional status at discharge, 16 (57 %) improved to good functional status at 6 months. All patients with Hunt-Hess grade 4 or 5 hemorrhages (n = 14) had poor functional status at discharge, but half (95 % CI, 20-80 %) recovered to a good functional status at 6 months.

CONCLUSIONS

Although our sample size is small, our findings suggest that a substantial proportion of patients with SAH who are disabled at discharge go on to regain functional independence within 6 months.

摘要

背景

尽管有大量关于蛛网膜下腔出血(SAH)后长期残疾的数据,但关于出院后功能恢复轨迹的数据很少。

方法

从 2009 年 10 月到 2010 年 4 月,我们前瞻性地随访了从一所大学医院出院的连续非创伤性 SAH 患者。通过病历回顾和标准化电话访谈,在出院时和 6 个月时计算改良 Rankin 量表(mRS)评分。良好的功能状态定义为 mRS 评分为 0-2,不良状态定义为 mRS 评分为 3-6。使用描述性统计来评估功能恢复的轨迹,并确定功能状态从不良改善为良好的患者比例。

结果

在 52 例非创伤性 SAH(79%为动脉瘤性)出院存活的患者中,大多数(71%)出院回家。出院时中位数(IQR)mRS 评分为 3(2-4),6 个月时为 2(1-2)。大多数患者(83%;95%CI,72-93%)出现了一些功能恢复(mRS 评分任何改善)。在出院时功能状态较差的 28 例患者中,有 16 例(57%)在 6 个月时改善为功能状态良好。所有(n=14)Hunt-Hess 分级 4 或 5 级出血的患者出院时功能状态较差,但有一半(95%CI,20-80%)在 6 个月时恢复为良好功能状态。

结论

尽管我们的样本量较小,但我们的发现表明,出院时残疾的 SAH 患者中有相当大的比例在 6 个月内恢复了功能独立性。

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本文引用的文献

1
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Lancet. 2012 Jul 7;380(9836):44-9. doi: 10.1016/S0140-6736(12)60724-7. Epub 2012 May 25.
2
Accuracy of neurovascular fellows' prognostication of outcome after subarachnoid hemorrhage.神经血管研究员对蛛网膜下腔出血后预后预测的准确性。
Stroke. 2012 Mar;43(3):702-7. doi: 10.1161/STROKEAHA.111.639161. Epub 2012 Jan 5.
3
Long-term outcomes of patients with aneurysmal subarachnoid haemorrhage.
动脉瘤性蛛网膜下腔出血:过去十年
Transl Stroke Res. 2021 Jun;12(3):428-446. doi: 10.1007/s12975-020-00867-0. Epub 2020 Oct 19.
4
Anemia prevalence and incidence and red blood cell transfusion practices in aneurysmal subarachnoid hemorrhage: results of a multicenter cohort study.动脉瘤性蛛网膜下腔出血的贫血患病率、发病率和红细胞输血实践:一项多中心队列研究的结果。
Crit Care. 2018 Jul 4;22(1):169. doi: 10.1186/s13054-018-2089-7.
5
Response of brain oxygen to therapy correlates with long-term outcome after subarachnoid hemorrhage.脑氧对治疗的反应与蛛网膜下腔出血后的长期预后相关。
Neurocrit Care. 2013 Dec;19(3):320-8. doi: 10.1007/s12028-013-9890-6.
6
Childhood basilar artery occlusion: a report of 5 cases and review of the literature.儿童基底动脉闭塞:5例报告及文献复习
J Child Neurol. 2014 May;29(5):633-45. doi: 10.1177/0883073813488826. Epub 2013 May 13.
7
What is new in neurocritical care: 2012.神经重症监护领域的新进展:2012年
Intensive Care Med. 2013 Mar;39(3):387-8. doi: 10.1007/s00134-013-2843-x.
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Lancet Neurol. 2011 Apr;10(4):349-56. doi: 10.1016/S1474-4422(11)70017-5.
4
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5
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Cerebrovasc Dis. 2010;30(4):423-31. doi: 10.1159/000317078. Epub 2010 Aug 18.
6
Cognitive and functional outcome after aneurysmal subarachnoid hemorrhage.颅内动脉瘤性蛛网膜下腔出血的认知和功能结局。
Stroke. 2010 Aug;41(8):e519-36. doi: 10.1161/STROKEAHA.110.581975. Epub 2010 Jul 1.
7
Improving modified Rankin Scale assessment with a simplified questionnaire.使用简化问卷改善改良 Rankin 量表评估。
Stroke. 2010 May;41(5):1048-50. doi: 10.1161/STROKEAHA.109.571562. Epub 2010 Mar 11.
8
Predictors of global cognitive impairment 1 year after subarachnoid hemorrhage.蛛网膜下腔出血 1 年后发生全球认知障碍的预测因素。
Neurosurgery. 2009 Dec;65(6):1043-50; discussion 1050-1. doi: 10.1227/01.NEU.0000359317.15269.20.
9
Changes in case fatality of aneurysmal subarachnoid haemorrhage over time, according to age, sex, and region: a meta-analysis.根据年龄、性别和地区,动脉瘤性蛛网膜下腔出血的病死率随时间的变化:一项荟萃分析。
Lancet Neurol. 2009 Jul;8(7):635-42. doi: 10.1016/S1474-4422(09)70126-7. Epub 2009 Jun 6.
10
Cognitive outcome after aneurysmal subarachnoid hemorrhage: time course of recovery and relationship to clinical, radiological, and management parameters.动脉瘤性蛛网膜下腔出血后的认知结果:恢复的时间进程及其与临床、影像学和管理参数的关系。
Neurosurgery. 2007 Apr;60(4):649-56; discussion 656-7. doi: 10.1227/01.NEU.0000255414.70807.A0.